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103198-43-2

3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)eth oxy]methyl]-1,4-dihydro-6-methyl-, 3-ethyl 5-(1-methylethyl) ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)eth oxy]methyl]-1,4-dihydro-6-methyl-, 3-ethyl 5-(1-methylethyl) ester

    Cas No: 103198-43-2

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  • 103198-43-2 Structure

  • Basic information

    1. Product Name: 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)eth oxy]methyl]-1,4-dihydro-6-methyl-, 3-ethyl 5-(1-methylethyl) ester
    2. Synonyms:
    3. CAS NO:103198-43-2
    4. Molecular Formula: C30H30Cl2N2O7
    5. Molecular Weight: 601.483
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 103198-43-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)eth oxy]methyl]-1,4-dihydro-6-methyl-, 3-ethyl 5-(1-methylethyl) ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)eth oxy]methyl]-1,4-dihydro-6-methyl-, 3-ethyl 5-(1-methylethyl) ester(103198-43-2)
    11. EPA Substance Registry System: 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)eth oxy]methyl]-1,4-dihydro-6-methyl-, 3-ethyl 5-(1-methylethyl) ester(103198-43-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 103198-43-2(Hazardous Substances Data)

103198-43-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 103198-43-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,1,9 and 8 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 103198-43:
(8*1)+(7*0)+(6*3)+(5*1)+(4*9)+(3*8)+(2*4)+(1*3)=102
102 % 10 = 2
So 103198-43-2 is a valid CAS Registry Number.

103198-43-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(2,3-Dichloro-phenyl)-2-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethoxymethyl]-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-isopropyl ester

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103198-43-2 SDS

103198-43-2Relevant articles and documents

Long-acting dihydropyridine calcium antagonists. 9. Structure activity relationships around amlodipine

Alker, D,Arrowsmith, JE,Campbell, SF,Cross, PE

, p. 907 - 913 (2007/10/02)

The preparation of a range of 1,4-dihydropyridine analogues of amlodipine has been undertaken and their calcium antagonist activities on rat aorta have been evaluated.Increasing the size of the C5 ester group dramatically reduces calcium antagonist activity, a trend which would be compatible with the carbonyl group of that ester binding to the DHP receptor.Amlodipine analogues with extended C3 ester substituents also have lower potency than amlodipine, possibly because of disruption of a favourable interaction between the protonated amino group on the 2-substituentand the DHP receptor.Replacement of the 6-methyl substituent in amlodipine by alkoxyalkyl groups or electron-withdrawing groups is also detrimental to calcium antagonist activity. amlodipine / 1,4-dihydropyridine / structure activity relationship

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