1032231-28-9

Basic information

• Product Name: 5-bromo-2-cyanobenzoic acid
• Synonyms: 5-bromo-2-cyanobenzoic acid;BENZOIC ACID, 5-BROMO-2-CYANO-;4-Bromo-2-carboxybenzonitrile
• CAS NO: 1032231-28-9
• Molecular Formula: C₈H₄BrNO₂
• Molecular Weight: 226
• Mol File: 1032231-28-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 169-171 °C (decomp)
• Boiling Point: 379.1±32.0 °C(Predicted)
• Appearance: /
• Density: 1.82±0.1 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.75±0.10(Predicted)
• CAS DataBase Reference: 5-bromo-2-cyanobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-cyanobenzoic acid(1032231-28-9)
• EPA Substance Registry System: 5-bromo-2-cyanobenzoic acid(1032231-28-9)

Safety Data

• RIDADR: 3439
• HazardClass: 6.1
• PackingGroup: Ⅲ
• Hazardous Substances Data: 1032231-28-9(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-cyanobenzoic acid is a chemical compound with the molecular formula C8H4BrNO2. It is a white to off-white crystalline powder that is soluble in organic solvents such as dichloromethane and dimethyl sulfoxide. 5-Bromo-2-cyanobenzoic acid is used in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. It is also used as a building block for the preparation of various heterocycles and biologically active compounds. Additionally, 5-Bromo-2-cyanobenzoic acid has been studied for its potential anti-cancer and anti-inflammatory properties, making it a subject of interest in medicinal chemistry research.

Upstream product

• 124-38-9 carbon dioxide 
• 623-00-7 4-bromobenzenecarbonitrile 

Downstream Products

• 127510-93-4 5-bromo-2-cyanobenzoic acid ethyl ester 

Relevant articles and documents

C- ARYL GLYCOSID DERIVATIVES, PHARMACEUTICAL COMPOSITION, PREPARATION PROCESS AND USES THEREOF

This invention relates to a kind of C-aryl glycoside derivatives, its pharmaceutical compositions, preparation methods, and uses thereof. The preparation method comprises: method 1: in a solvent, deprotecting the acetyl protecting groups of compound 1-f in the presence of a base; method 2: 1) compound 2-g reacts with via Mitsunobu reaction; 2) deprotecting the acetyl protecting groups of compound 2-f obtained from step 1; method 3: 1) compound 2-g reacts with via nucleophilic substitution reaction; 2) deprotecting the acetyl protecting groups of compound 3-f obtained from step 1. The pharmaceutical composition comprises a kind of C-aryl glycoside derivatives; it's pharmaceutically acceptable salts and/or prodrugs thereof and excipient thereof. This invention further relates to a kind of C-aryl glycoside derivatives, it's pharmaceutically acceptable salts or pharmaceutical compositions thereof for the use in preparation of a SGLT inhibitor. The C-aryl glycoside derivatives of this invention provides a new direction for the study of SGLT inhibitors.