103234-38-4Relevant academic research and scientific papers
Design, Conformation, and Crystallography of 2-Naphthyl Phenyl Ethers as Potent Anti-HIV Agents
Lee, Won-Gil,Chan, Albert H.,Spasov, Krasimir A.,Anderson, Karen S.,Jorgensen, William L.
supporting information, p. 1156 - 1160 (2016/12/16)
Catechol diethers that incorporate a 7-cyano-2-naphthyl substituent are reported as non-nucleoside inhibitors of HIV-1 reverse transcriptase (NNRTIs). Many of the compounds have 1-10 nM potencies toward wild-type HIV-1. An interesting conformational effect allows two unique conformers for the naphthyl group in complexes with HIV-RT. X-ray crystal structures for 4a and 4f illustrate the alternatives.
Photocleavable molecule for laser desorption ionization mass spectrometry
Maki, Toshihide,Ishida, Koji
, p. 6427 - 6433 (2008/02/10)
(Figure Presented) A new photocleavable molecule for laser desorption ionization mass spectrometry (LDI-MS) was designed and synthesized. The molecule exhibited high sensitivity for negative mode MS detection with good chemical stability. The molecule was successfully applied to molecular tag for (LDI-MS). Kinetic measurement of the amidation reaction and monitoring of aminolysis of acetylated sugars were demonstrated with the molecular tag.
Herbicidal cyclohexane-1,3-dione derivatives
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, (2008/06/13)
The invention concerns novel compounds of the formula I and isomers thereof STR1 wherein: n is an integer selected from 2 to 4; m is zero or an integer selected from 1 to 3; X, which may be the same or different, are independently selected from halogen, a
