1032350-06-3

Basic information

• Product Name: Tert-Butyl1-(4-Bromophenyl)cyclobutylcarbamate
• Synonyms: Tert-Butyl1-(4-Bromophenyl)cyclobutylcarbamate;tert-butyl N-[1-(4-bromophenyl)cyclobutyl]carbamate;1-(BOC-AMINO)-1-(4-BROMOPHENYL)-CYCLOBUTANE;[1-(4-bromophenyl)cyclobutyl]carbamic acid tert-butyl ester;2-Methyl-2-propanyl [1-(4-bromophenyl)cyclobutyl]carbamate
• CAS NO: 1032350-06-3
• Molecular Formula: C₁₅H₂₀BrNO₂
• Molecular Weight: 326.2288
• Mol File: 1032350-06-3.mol

Chemical Properties

• Boiling Point: 400.5±34.0 °C(Predicted)
• Appearance: /
• Density: 1.33±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 11.82±0.20(Predicted)
• CAS DataBase Reference: Tert-Butyl1-(4-Bromophenyl)cyclobutylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: Tert-Butyl1-(4-Bromophenyl)cyclobutylcarbamate(1032350-06-3)
• EPA Substance Registry System: Tert-Butyl1-(4-Bromophenyl)cyclobutylcarbamate(1032350-06-3)

Safety Data

• Hazardous Substances Data: 1032350-06-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Tert-Butyl1-(4-Bromophenyl)cyclobutylcarbamate is used as a potential active pharmaceutical ingredient for the development of new drugs. Its unique structure may offer specific reactivity and biological activity that could be harnessed for therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, Tert-Butyl1-(4-Bromophenyl)cyclobutylcarbamate may be utilized as a component in the formulation of pesticides or other crop protection products. Its chemical properties could contribute to the effectiveness of these products in managing pests and diseases in agriculture.

Upstream product

• 75-65-0 tert-butyl alcohol 
• 133017-10-4 Butyl 2-(4-bromophenyl)acetate 
• 485828-58-8 1-(4- bromophenyl)cyclobutane-1-carbonitrile 
• 16532-79-9 4-Bromophenylacetonitrile 
• 1193389-40-0 1-(4-bromophenyl)cyclobutane-1-amine hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1094218-30-0 1-(4-bromophenyl)cyclobutanamine 
• 1032350-05-2 1-(4-bromophenyl)cyclobutanecarboxylic acid amide 

Downstream Products

• 1032528-06-5 {1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclobutyl}-carbamic acid tert.-butyl ester 
• 1356002-02-2 tert-butyl {1-[4-(5-methyl-3-phenylimidazo[1,2-a]pyridin-2-yl)phenyl]cyclobutyl}carbamate 
• 1247894-84-3 1-[4-(6-phenyl-imidazo[1,2-a]pyrimidin-7-yl)phenyl]cyclobutylamine 
• 1355239-60-9 1-[4-(2-methyl-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl)phenyl]cyclobutylamine 
• 1355239-62-1 {7-[4-(1-amino-cyclobutyl)phenyl]-6-phenyl-imidazo[1,2-a]pyrimidin-5-yl}cyclopropylamine 
• 1355239-74-5 {5-[4-(1-aminocyclobutyl)phenyl]-6-phenyl-2-pyridine-2-yl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}tert-butylamine 
• 1355239-89-2 1-{4-[3-(4-methansulfonyl-phenyl)-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl]phenyl}cyclobutylamine 
• 1247897-89-7 {1-[4-(3-bromo-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl)phenyl]cyclobutyl}carbamic acid tert-butyl ester 
• 1355240-89-9 (1-{4-[3-(4-methanesulfonyl-phenyl)-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl]phenyl}cyclobutyl)carbamic acid tert-butyl ester 
• 1355240-23-1 1-{4-[3-(4-fluorophenyl)-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl]phenyl}cyclobutylamine 
• 1355240-37-7 {1-[4-(2-methyl-6-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)phenyl]cyclobutyl}carbamic acid tert-butyl ester 
• 1247897-86-4 {1-[4-(6-phenyl-imidazo[1,2-a]pyrimidin-7-yl)phenyl]cyclobutyl}carbamic acid tert-butyl ester 
• 1355240-42-4 {1-[4-(2-methyl-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl)phenyl]cyclobutyl}carbamic acid tert-butyl ester 
• 1355240-44-6 {1-[4-(5-cyclopropylamino-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl)phenyl]cyclobutyl}carbamic acid tert-butyl ester 

Relevant articles and documents

ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

A compound of formula (I): wherein the substituents are as defined in the description. Medicinal products containing the same which are useful in treating or preventing pathologies which are the result of activation of the RhoA/ROCK pathway and phosphorylation of the myosin light chain.

General and cost-effective synthesis of 1-heteroaryl/arylcycloalkylamines and their broad applications

A general and cost-effective route has been developed to synthesize 1-heteroarylsubstituted cycloalkylamines from readily available heteroarylacetate in good yields. This synthesis features a LHMDS promoted cyclization and one-pot hydrolysis/Curtius rearr

ANTITUMOR EFFECT POTENTIATOR COMPOSED OF IMIDAZOOXAZINE COMPOUND

An antitumor effect potentiator for potentiating one or more other antitumor agents, comprising, as an active ingredient, an imidazooxazine compound represented by Formula (I), or a pharmaceutically acceptable salt thereof, wherein A, B, C, and D represen

PROCESS OF PREPARING 3-(3-(4-(1-AMINOCYCLOBUTYL)PHENYL)-5-PHENYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-YL)PYRIDIN-2-AMINE

The present invention is directed to a processes for the synthesis of 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine:

NOVEL IMIDAZO-OXAZINE COMPOUND OR SALT THEREOF

The present invention provides an imidazooxazine compound represented by Formula (I) or a salt thereof, wherein A, B, C, and D are as defined in the specification.

SUBSTITUTED IMIDAZOPYRAZINES AS AKT KINASE INHIBITORS

Compounds of formula (I) which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.

SUBSTITUTED PYRAZOLOPYRIMIDINES AS AKT KINASE INHIBITORS

Compounds of formula (I) which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.

BICYCLIC PYRIMIDINES

Compounds of formula (I), which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.

IMIDAZOPYRIDAZINES AS AKT KINASE INHIBITORS

Imidazopyridazines of formula (I) a process for their production and the use thereof.

SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AND -PYRIDINES

Compounds of formula (I) which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.