10324-65-9

Upstream product

• 1056477-06-5 2-bromocyclohexanone 
• 10316-66-2 2-hydroxy-2-cyclohexen-1-one 
• 108-94-1 cyclohexanone 
• 765-87-7 cyclohexane-1,2-dione 

Downstream Products

• 445249-11-6 3-bromo-2-methoxycyclohex-2-en-1-one 
• 445249-12-7 3-Bromo-1-((E)-hepta-4,6-dienyl)-2-methoxy-cyclohex-2-enol 
• 89114-50-1 2-methoxy-3-phenylcyclohex-2-en-1-one 
• 1088713-97-6 ethyl 2-(2-fluoro-4-iodophenylamino)-7-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxylate 
• 1088714-05-9 ethyl 2-(4-bromo-2-fluorophenylamino)-7-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxylate 

Relevant academic research and scientific papers

Catalytic oxidations of enolizable ketones using 2-alkylidene-4- oxothiazolidine vinyl bromide

Direct oxidation of enolizable ketones to α-hydroxy derivatives, vicinal dicarbonyls or tricarbonyl compounds has been achieved by a catalytic amount of 2-alkylidene-4-oxothiazolidine vinyl bromide in DMSO as a solvent. The yields range from moderate to good.

Sonogashira cross-coupling of 3-bromo-1,2-diones: An access to 3-alkynyl-1,2-diones

A new general method for the synthesis of enols of cyclic 3-alkynyl-substituted 1,2-diketones is developed. Sonogashira cross-coupling of silyl enolates of cyclic 3-bromo-cyclopentane- and 3-bromo-cyclohexane-1,2-diones with variety of substituted acetylenes afforded enols of cyclic 3-alkynyl-1,2-diones with good yields (up to 93%) in a short reaction time. The starting 3-bromo-1,2-diones are easily obtainable by direct bromination of 1,2-diones with NBS.

FUNGICIDAL HETEROCYCLIC COMPOUNDS

Disclosed are compounds of Formula 1, including all geometric and stereoisomers, tautomers, N-oxides, and salts thereof, wherein E, X, Y, G, Z and Q are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.

Intramolecular 4+3 cycloadditions. A cyclohexenyl cation, its halogenated congener and a quasi-Favorskii rearrangement

Treatment of alkoxycyclohexenols bearing a tethered diene substituent with a Lewis acid results in intramolecular 4+3 cycloaddition with complete endo selectivity. A cycloadduct bearing a bromo substituent at a bridgehead position undergoes a quasi-Favorskii rearrangement in near quantitative yield upon reaction with lithium aluminum hydride.