103244-32-2Relevant academic research and scientific papers
Novel 2′-alkoxymethyl substituted klavuzon derivatives as inhibitors of Topo I and CRM1
?etinkaya, Hakk?,Y?ld?z, Mehmet S.,Kutluer, Meltem,Alkan, Aylin,Ozan Ota?, Hasan,?a??r, Ali
, (2020)
In this work, 2′-alkoxymethyl substituted klavuzon derivatives were prepared starting from 2-methyl-1-naphthoic acid in eight steps. Anticancer potencies of the synthesized compounds were evaluated by performing MTT cell viability test over cancerous and
Liquid Chromatographic Optical Resolution of 2,2'-Spirobibenzindan Derivatives and Absolute Stereochemistry as Determined by the C.D. Exciton Chirality Method
Harada, Nobuyuki,Iwabuchi, Jun,Yokota, Yoichi,Uda, Hisashi,Okamoto, Yoshio,et al.
, p. 1845 - 1848 (2007/10/02)
2,2'-Spirobibenzindan derivatives, (1) and (2) have been synthesized and optically resolved by means of liquid chromatography using a column with a chiral stationary phase of (+)-poly(triphenylmethyl methacrylate); the absolute stereochemistry of each enantiomer was unambiguously determined by the c.d. exciton chirality method.
