103247-78-5

Basic information

• Product Name: 1-Trimethylsilyl-4-phenyl-2-azetidinon
• CAS NO: 103247-78-5
• Molecular Weight: 219.359
• Mol File: 103247-78-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Trimethylsilyl-4-phenyl-2-azetidinon(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Trimethylsilyl-4-phenyl-2-azetidinon(103247-78-5)
• EPA Substance Registry System: 1-Trimethylsilyl-4-phenyl-2-azetidinon(103247-78-5)

Safety Data

• Hazardous Substances Data: 103247-78-5(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 17599-61-0 N-benzylidene-1,1,1-trimethylsilanamine 
• 141-78-6 ethyl acetate 

Downstream Products

• 5661-55-2 4-phenylazetidin-2-one 

Relevant articles and documents

N-Trimethylsilyl Imines: Applications to the Synthesis of β-Lactams

Ester enolates and N-trimethylsilyl imines react to afford N-protio-β-lactams.The stereochemical course of the reaction depends on the ester enolate geometry.Therefore (E)-enolates give mainly cis β-lactams while (Z)-enolates give nearly equal mixtures of cis and trans β-lactams.The use of ethyl β-hydroxybutyrate as the ester component allows the preparation of β-lactams of potential use in carbapenem synthesis.The differences in the behavior of N-trimethylsilyl and N-aryl imines in ester-imine condensations are also discussed.