103274-64-2

Upstream product

• 197514-04-8 4-chloro-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzoic acid 

Downstream Products

• 2642-63-9 3',4'-dichloroacetophenone 
• 857560-77-1 1-(2-amino-4-chloro-5-nitro-phenyl)-ethanone 
• 857560-79-3 1-(2-amino-4-chloro-3-nitro-phenyl)-ethanone 
• 5465-65-6 4-chloro-3-nitroacetophenone 
• 18514-94-8 6,7-dichloro-1H-cinnolin-4-one 
• 96228-48-7 2-acetamido-4-chloro-5-nitroacetophenone 
• 855929-69-0 acetic acid-(6-acetyl-3-chloro-2-nitro-anilide) 
• 2540-09-2 7-chloro-4-methyl-quinolin-2-ol 

Relevant academic research and scientific papers

2-aryl-2,3-dihydro-4(1H)-quinolinone semicarbazone compound and application thereof

The invention relates to the field of medicine technology, and a series of novel 2-aryl-2,3-dihydrogen-4(1H)-quinolinone semicarbazone derivatives (I) and pharmaceutically acceptable salts, solvates,optical isomers or polymorphs are designed and synthesized. The derivative (I) and its pharmaceutically acceptable salt, solvate, optical isomer or polymorph can be mixed as an active ingredient witha pharmaceutically acceptable carrier to prepare a pharmaceutical composition. A double dilution method is used for test of the antifungal activity of the derivative (I) and its pharmaceutically acceptable salt, solvate, optical isomer or polymorph, and the results show that the derivative has stronger killing effect on clinically common pathogenic fungi, and is expected to overcome the defects oflarge toxic and side effects, easy generation of drug resistance of azole antifungal medicines which are widely used clinically. The specific formula is shown in the description.