103275-21-4

Basic information

• Product Name: 3-BroMo-4-(tert-butyl)aniline
• Synonyms: 3-BroMo-4-(tert-butyl)aniline
• CAS NO: 103275-21-4
• Molecular Formula: C₁₀H₁₄BrN
• Molecular Weight: 228.12886
• Mol File: 103275-21-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 29-29.5 °C
• Boiling Point: 125 °C(Press: 1 Torr)
• Appearance: /
• Density: 1.306±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 3.85±0.10(Predicted)
• CAS DataBase Reference: 3-BroMo-4-(tert-butyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BroMo-4-(tert-butyl)aniline(103275-21-4)
• EPA Substance Registry System: 3-BroMo-4-(tert-butyl)aniline(103275-21-4)

Safety Data

• Hazardous Substances Data: 103275-21-4(Hazardous Substances Data)

Usage

General Description

3-Bromo-4-(tert-butyl)aniline is a chemical compound with the molecular formula C10H14BrN. It is a substituted aniline derivative, with a bromine atom attached to the 3rd carbon and a tert-butyl group attached to the 4th carbon of the aniline ring. 3-BroMo-4-(tert-butyl)aniline is often used in organic synthesis and pharmaceutical research as a building block for the production of various organic compounds. It may also be used in the production of dyes and pigments, as well as in the development of new materials with specific properties. Its structure and reactivity make it a valuable tool for the synthesis of complex organic molecules. Additionally, 3-Bromo-4-(tert-butyl)aniline may have potential applications in the field of medicinal chemistry due to its structural features.

Upstream product

• 101655-17-8 3-bromo-4-tert-butyl-benzoic acid amide 
• 6310-17-4 2-bromo-1-tert-butyl-4-nitrobenzene 
• 253185-03-4 tert-butylbenzene 
• 3282-56-2 4-tert-butylnitrobenzene 
• 98-73-7 4-(1,1-dimethylethyl)benzoic acid 
• 38473-89-1 3-bromo-4-(tert-butyl)benzoic acid 

Downstream Products

• 7073-99-6 2-tert-butylbromobenzene 
• 14034-88-9 5-Methoxy-2-tert.-butyl-benzoesaeure 
• 14034-13-0 2-bromo-1-(tert-butyl)-4-methoxybenzene 
• 14034-12-9 3-bromo-4-(tert-butyl)phenol 
• 6683-76-7 2,4-dibromo-1-tert-butyl-benzene 
• 1077-58-3 2-tert-butylbenzoic acid 
• 861858-26-6 5-bromo-4-tert-butyl-2-iodo-phenylamine 

Relevant articles and documents

Nucleophilic Iron Complexes in Proton-Transfer Catalysis: An Iron-Catalyzed Dimroth Cyclocondensation

The nucleophilic iron complex Bu4N[Fe(CO)3(NO)] (TBA[Fe]) is an active catalyst in C?H-amination but also in proton-transfer catalysis. Herein, we describe the successful use of this complex as a proton-transfer catalyst in the cyclocondensation reaction between azides and ketones to the corresponding 1,2,3-triazoles. Cross-experiments indicate that the proton-transfer catalysis is significantly faster than the nitrene-transfer catalysis, which would lead to the C?H amination product. An example of a successful sequential Dimroth triazole–indoline synthesis to the corresponding triazole-substituted indolines is presented.

SUBSTITUTED UREA AND CARBAMATE, PHENACYL-2-HYDROXY-3-DIAMINOALKANE, AND BENZAMIDE-2-HYDROXY-3-DIAMINOALKANE ASPARTYL-PROTEASE INHIBITORS

The invention relates to acetyl 2-hydroxy-1,3-diaminospirocyclohexanes and derivatives thereof that are useful in treating at least one disease, disorder, and condition associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and condition associated with abnormal deposition of A-beta protein.