1033127-13-7

Basic information

• Product Name: [3-(4-{[(isopropoxycarbonyl)oxy]methoxy}phenyl)-3-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-1-yl]methyl isopropyl carbonate
• Synonyms: [3-(4-{[(isopropoxycarbonyl)oxy]methoxy}phenyl)-3-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-1-yl]methyl isopropyl carbonate
• CAS NO: 1033127-13-7
• Molecular Weight: 563.604
• Mol File: 1033127-13-7.mol

Chemical Properties

• CAS DataBase Reference: [3-(4-{[(isopropoxycarbonyl)oxy]methoxy}phenyl)-3-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-1-yl]methyl isopropyl carbonate(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(4-{[(isopropoxycarbonyl)oxy]methoxy}phenyl)-3-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-1-yl]methyl isopropyl carbonate(1033127-13-7)
• EPA Substance Registry System: [3-(4-{[(isopropoxycarbonyl)oxy]methoxy}phenyl)-3-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-1-yl]methyl isopropyl carbonate(1033127-13-7)

Safety Data

• Hazardous Substances Data: 1033127-13-7(Hazardous Substances Data)

Upstream product

• 258841-42-8 isopropyloxycarbonyloxymethyl iodide 
• 1033127-30-8 3-(4-hydroxyphenyl)-3-(4-methoxyphenyl)indolin-2-one 

Relevant articles and documents

PRODRUGS OF DIPHENYL OX- INDOL- 2 -ONE COMPOUNDS FOR THE TREATMENT OF CANCERS

The present application discloses prodrugs of substituted 3,3-diphenyl-l,3-dihydro-indol-2-one compounds having the general formula (I). The 4-position of the phenyl moieties and the N -position of the indole represent useful handles for the introduction of particular prodrug groups, in particular those comprising an amino acid moiety. The prodrug compounds are believed to be useful for the treatment of cancer in a mammal, possibly in combination with one or more other chemotherapeutic agents. The application also discloses the compounds for use in a method of treating a mammal suffering from or being susceptible to cancer.