1033127-30-8

Basic information

• Product Name: 3-(4-hydroxyphenyl)-3-(4-methoxyphenyl)indolin-2-one
• Synonyms: 3-(4-hydroxyphenyl)-3-(4-methoxyphenyl)indolin-2-one
• CAS NO: 1033127-30-8
• Molecular Weight: 331.371
• Mol File: 1033127-30-8.mol

Chemical Properties

• CAS DataBase Reference: 3-(4-hydroxyphenyl)-3-(4-methoxyphenyl)indolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-hydroxyphenyl)-3-(4-methoxyphenyl)indolin-2-one(1033127-30-8)
• EPA Substance Registry System: 3-(4-hydroxyphenyl)-3-(4-methoxyphenyl)indolin-2-one(1033127-30-8)

Safety Data

• Hazardous Substances Data: 1033127-30-8(Hazardous Substances Data)

Upstream product

• 111500-91-5 3-hydroxy-3-(4-methoxyphenyl)-1,3-dihydro-2H-indol-2-one 
• 108-95-2 phenol 

Downstream Products

• 1033127-26-2 C₂₆H₂₅NO₆ 
• 1033127-13-7 [3-(4-{[(isopropoxycarbonyl)oxy]methoxy}phenyl)-3-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-1-yl]methyl isopropyl carbonate 

Relevant articles and documents

Friedel-Crafts alkylations of electron-rich aromatics with 3-hydroxy-2-oxindoles: Scope and limitations

A Lewis acid-catalyzed nucleophilic addition of electron rich aromatics with 3-hydroxy-2-oxindoles 5 was developed. The reaction is believed to proceed through the 2H-indol-2-one ring system 9, which eventually reacts with various electron-rich aromatics to afford a variety of 2-oxindoles with an all-carbon quaternary center at the pseudobenzylic position (4, 8, 13, and 16) in high yields. The methodology provides an expeditious route to the tetracyclic core (3) of diazonamide (1), and azonazine (2) as well as the tricyclic core of asperazine (6a), idiospermuline (6b), and calycosidine (6c) viz. C(3a)-arylpyrroloindolines 7 having an all-carbon quaternary center on further synthetic elaboration.