103339-87-3Relevant academic research and scientific papers
An efficient method for the synthesis of phenacyl ester-protected dipeptides using neutral alumina-supported sodium carbonate 'Na2CO3/n-Al2O3'
Hashimoto, Chikao,Sugimoto, Kazuhiro,Takahashi, Youhei,Kodomari, Mitsuo
, p. 659 - 662 (2013/09/23)
In the synthesis of dipeptides (Boc-AA1-AA2-OPac: AA1 and AA2 represent amino acids) protected by phenacyl (Pac) ester, amines and solid bases as the base for the conversion of the trifluoroacetic acid (TFA) sal
Intramolecular triplet-triplet energy transfer in short flexible bichromophoric amino acids, dipeptides and carboxylic acid diester
Zabadal, Miroslav,Heger, Dominik,Klan, Petr,Kriz, Zdenek
, p. 776 - 796 (2007/10/03)
Efficiencies of the intramolecular triplet-triplet energy transfer (ITET) in various bichromophoric amino acids (glycine, valine, phenylalanine, and sarcosine), dipeptides (glycylglycine, phenylalanylphenylalanine), and a simple diester, with the benzoyl
Design of the Synthetic Route for Peptides and Proteins Based on the Solubility Prediction Method. I. Synthesis and Solubility Properties of Human Proinsulin C-Peptide Fragments
Narita Mitsuaki,Ogura, Toshihiko,Sato, Kazuhiro,Honda, Shinya
, p. 2433 - 2438 (2007/10/02)
The usefulness of the solubility prediction method is demonstrated using relatively small peptide fragments of human proinsulin C-peptide.The propriety of the solubility prediction method for peptides having polar side chains is also examined in the following respects: (1) Peptide intermediates smaller than a heptapeptide have high solubility regardless of their c> values; (2) the c> values of peptide intermediates are useful for judging solubility of peptide intermediates equal to or larger than an octapeptide level; (3) the Pro residue in a central position of a peptide chain is effective for increasing peptide solubility; and (4) there is critical chain length for peptide insolubility caused by a β-sheet aggregation.A strategy suitable for the design of the synthetic route or human proinsulin C-peptide is subsequently discussed on the basis of the solubility prediction of peptide intermediates.
