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31972-52-8

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31972-52-8 Usage

Chemical Properties

White powder

Check Digit Verification of cas no

The CAS Registry Mumber 31972-52-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,9,7 and 2 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 31972-52:
(7*3)+(6*1)+(5*9)+(4*7)+(3*2)+(2*5)+(1*2)=118
118 % 10 = 8
So 31972-52-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H16N2O5/c1-9(2,3)16-8(15)11-4-6(12)10-5-7(13)14/h4-5H2,1-3H3,(H,10,12)(H,11,15)(H,13,14)

31972-52-8 Well-known Company Product Price

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  • Alfa Aesar

  • (H62889)  N-Boc-glycylglycine, 97%   

  • 31972-52-8

  • 5g

  • 882.0CNY

  • Detail
  • Alfa Aesar

  • (H62889)  N-Boc-glycylglycine, 97%   

  • 31972-52-8

  • 25g

  • 3528.0CNY

  • Detail

31972-52-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(tert-Butoxycarbonyl)glycylglycine

1.2 Other means of identification

Product number -
Other names 2-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]acetyl]amino]acetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:31972-52-8 SDS

31972-52-8Relevant articles and documents

Light-responsive peptide [2]rotaxanes as gatekeepers of mechanised nanocontainers

Martinez-Cuezva,Valero-Moya,Alajarin,Berna

, p. 14501 - 14504 (2015)

Novel mechanized silica nanoparticles incorporating a peptide-based molecular shuttle as a photo-responsive interlocked gatekeeper of nanocontainers are described including the uptake and delivery studies of a model cargo.

Side-chain glycylglycine-based polymer for simultaneous sensing and removal of copper(II) from aqueous medium

Choudhury, Neha,Mete, Sourav,Kambalapalli, Srikanth,De, Priyadarsi

, p. 914 - 921 (2018)

Since glycylglycine (Gly-Gly) residue in the N-terminal region of human prion protein, a copper binding protein, binds with Cu(II), N-terminus Gly-Gly side-chain containing water soluble block copolymer was synthesized and used for simultaneous sensing an

Purification-Free Method for Preparing Technetium-99m-Labeled Multivalent Probes for Enhanced in Vivo Imaging of Saturable Systems

Mizuno, Yuki,Uehara, Tomoya,Hanaoka, Hirofumi,Endo, Yota,Jen, Chun-Wei,Arano, Yasushi

, p. 3331 - 3339 (2016)

Metallic radionuclides provide target-specific radiolabeled probes for molecular imaging in radiochemical yields sufficient for administration to subjects without purification. However, unlabeled ligands in the injectate can compete for targeted molecules with radiolabeled probes, which eventually necessitates postlabeling purification. Herein we describe a "1 to 3" design to circumvent the issue by taking advantage of inherent coordination properties of technetium-99m (99mTc). A monovalent RGD ligand possessing an isonitrile as a coordinating moiety (CN-RGD) was reacted with [99mTc(CO)3(OH2)3]+ to prepare [99mTc(CO)3(CN-RGD)3]+ in over 95% radiochemical yields. This complex exhibited higher integrin αvβ3 binding affinity than its unlabeled monovalent ligand, primarily due to its multivalency. This compound visualized a murine tumor without removing unlabeled ligands, while a 99mTc-labeled monovalent probe derived from a monovalent ligand could not. The metal coordination-mediated synthesis of radiolabeled multivalent probes thereby can be a useful approach for preparing ready-to-use target-specific probes labeled with 99mTc and other metallic radionuclides of interest.

Synthesis of Vitamin B12-Antibiotic Conjugates with Greatly Improved Activity against Gram-Negative Bacteria

Zhao, Sheng,Wang, Zhi-Peng,Wen, Xumei,Li, Siyu,Wei, Guoxing,Guo, Jian,He, Yun

, p. 6632 - 6636 (2020)

There is an urgent need to discover new antibiotics and improve the efficacy of known antibiotics against Gram-negative bacteria. "Trojan horse"conjugates are novel and promising antibiotics. Herein we report the design and synthesis of vitamin-B12-ampicillin conjugates, which exhibited more than 500 times improved activity against Escherichia coli compared with ampicillin itself. Our studies demonstrate that the vitamin-B12 uptake pathway could be employed for effective antibiotic delivery and efficacy enhancement.

An effective and safe enkephalin analog for antinociception

Durgarao Viswanadham,B?ttger, Roland,Hohenwarter, Lukas,Nguyen, Anne,Rouhollahi, Elham,Smith, Alexander,Tsai, Yi-Hsuan,Chang, Yuan-Yu,Ortiz, Christopher Llynard,Yang, Lee-Wei,Jimenez, Liliana,Li, Siyuan,Hur, Chan,Li, Shyh-Dar

, (2021/07/10)

Opioids account for 69,000 overdose deaths per annum worldwide and cause serious side effects. Safer analgesics are urgently needed. The endogenous opioid peptide Leu-Enkephalin (Leu-ENK) is ineffective when introduced peripherally due to poor stability a

Synthesis of Histidine-Containing Oligopeptides via Histidine-Promoted Peptide Ligation

Huang, Kai-Jin,Huang, Yi-Chen,Lin, Yuya A.

supporting information, p. 400 - 403 (2018/02/21)

Histidine-containing peptides are valuable therapeutic agents for a treatment of neurodegenerative diseases. However, the synthesis of histidine-containing peptides is not trivial due to the potential of imidazole sidechain of histidine to act as a nucleophile if unprotected. A peptide ligation method utilizing the imidazole sidechain of histidine has been developed. The key imidazolate intermediate that acts as an internal acyl transfer catalyst during ligation is generated by deprotonation. Transesterification with amino acids or peptides tethered with C-terminal thioester followed by N→N acyl shifts led to the final ligated products. A range of histidine-containing dipeptides could be synthesized in moderate to good yields via this method without protecting the imidazole sidechain. The protocol was further extended to tripeptide synthesis via a long-range N→N acyl transfer, and tetrapeptide synthesis.

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