103367-97-1Relevant articles and documents
Synthetic Studies Directed toward the Naturally Occurring Acyl Tetramic Acids. 1. Covergent Total Synthesis of (+/-)-Tirandamycin A
Boeckman, Robert K.,Starrett, John E.,Nickell, David G.,Sum, P.-E.
, p. 5549 - 5559 (1986)
An efficient convergent synthetic approach to the structurally unusual tetramic acid antibiotic tirandamycin A is described.Among the key features is the use of a rigid substituted cyclohexanone derivative as a vehicle to assure control of the relative st