1033804-87-3

Upstream product

• 1033804-85-1 5-[2-(2,2,2-trifluoro-1-hydroxyethyl)phenyl]pyridine-2-carbonitrile 
• 1033804-86-2 (S)-3-[4-(2-amino-6-chloropyrimidin-4-yl)phenyl]-2-{[(tert-butoxy)carbonyl]amino}propanoic acid 
• 6630-33-7 ortho-bromobenzaldehyde 
• 741709-63-7 2-cyanopyridine-5-boronic acid pinacol ester 
• 1033804-84-0 5-(2-formylphenyl)pyridine-2-carbonitrile 

Downstream Products

• 1033804-83-9 (S)-2-amino-3-[4-(2-amino-6-{1-[2-(6-cyano-pyridin-3-yl)-phenyl]-2,2,2-tri-fluoro-ethoxy}-pyrimidin-4-yl)-phenyl]-propionic acid 

Relevant academic research and scientific papers

Based on 4 - phenyl -6 - (2, 2, 2 - trifluoro -1 - phenyl ethoxy) pyrimidine compound and its application method

The present invention relates to compounds based on 4-phenyl-6-(2,2,2-trifluoro-1-phenyl ethoxy) pyrimidine and an application method thereof, particularly discloses compounds of formula I and compositions comprising the compounds, and the application method thereof in treatment, prevention and / or management of diseases or disorders.

4-PHENYL-6-(2,2,2-TRIFLUORO-1-PHENYLETHOXY)PYRIMIDINE-BASED COMPOUNDS AND METHODS OF THEIR USE

Compounds of formula I are disclosed, as well as compositions comprising them and methods of their use to treat, prevent and/or manage diseases and disorders: