1033859-80-1

Upstream product

• 1033865-70-1 (2-bromothiazol-4-ylmethyl)(4-fluorophenyl)amine 
• 3282-30-2 pivaloyl chloride 

Downstream Products

• 1033859-90-3 N-(4-fluorophenyl)-2,2-dimethyl-N-{[2-(4-pyridin-2-ylpiperazin-1-yl)-1,3-thiazol-4-yl]methyl}propanamide 
• 1033858-99-9 N-{[2-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-1,3-thiazol-4-yl]methyl}-N-(4-fluorophenyl)-2,2-dimethylpropanamide 
• 1033859-01-6 N-(4-fluorophenyl)-N-({2-[3-(hydroxymethyl)piperidin-1-yl]-1,3-thiazol-4-yl}methyl)-2,2-dimethylpropanamide 
• 1033859-03-8 N-(4-fluorophenyl)-2,2-dimethyl-N-[(2-quinolin-3-yl-1,3-thiazol-4-yl)methyl]propanamide 
• 1033859-94-7 N-(4-fluorophenyl)-2,2-dimethyl-N-{[2-(4-pyrimidin-2-ylpiperazin-1-yl)-1,3-thiazol-4-yl]methyl}propanamide 

Relevant academic research and scientific papers

ION CHANNEL MODULATORS

The present teachings provide compounds of Formula (I): and pharmaceutically acceptable salts, hydrates, and esters thereof, wherein Ar, R1, R2, R3, p, and X are defined herein. The present teachings also provide processes for producing said compounds and their pharmaceutically acceptable salts, hydrates and esters, and methods of treating a pathological condition or disorder, or alleviating a symptom thereof, using said compounds including their pharmaceutically acceptable salts, hydrates and esters. The compounds can be useful in modulating ion channel activity including treating a variety of conditions associated with the abnormal modulation of one or more voltage-gated calcium channels.