10339-60-3Relevant articles and documents
Total synthesis of the proposed structure of trichodermatide A
Myers, Eddie,Herrero-Gmez, Elena,Albrecht, Irina,Lachs, Jennifer,Mayer, Peter,Hanni, Matti,Ochsenfeld, Christian,Trauner, Dirk
, p. 9812 - 9817 (2014)
A short total synthesis of the published structure of racemic trichodermatide A is reported. Our synthesis involves a Knoevenagel condensation/Michael addition sequence, followed by the formation of tricyclic hexahydroxanthene-dione and a diastereoselective bis-hydroxylation. The final product, the structure of which was confirmed by X-ray crystallography, has NMR spectra that are very similar, but not identical, to those of the isolated natural product. Quantum chemically computed 13C shifts agree well with the present NMR measurements. (Chemical Equation Presented).
Wilson,Prodan
, p. 4231 (1976)
ALKYL SULFATES FROM THE ASCIDIAN Holocynthia roretzi
Fedorov, S. N.,Chumak, A. D.,Denisenko, V. A.,Stonik, V. A.,Isakov, V. V.
, p. 634 - 635 (1982)
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INTRAMOLECULAR HYDROSILATION OF ACETYLENES: REGIOSELECTIVE FUNCTIONALIZATION OF HOMOPROPARGYL ALCOHOLS
Tamao, Kohei,Maeda, Kimio,Tanaka, Tetsu,Ito, Yoshihiko
, p. 6955 - 6956 (1988)
Platinum-catalyzed intramolecular hydrosilation of hydrodimethylsilyl ethers of homopropargyl alcohols proceeds regioselectively in a 5-exo-dig mode.The resulting vinylsilanes can be transformed into 3-alkanon-1-ol and 3-bromo-3-alken-1-ol derivatives by H2O2 oxidation and bromine cleavage, respectively.
CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF
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Page/Page column 47; 69, (2021/06/26)
The present application discloses a compound of formula (I) or a salt thereof: (I) and compositions comprising such compound or salt thereof. The use of such compound, salt thereof or composition comprising same for treating anemia or leukopenia, fibrosis, cancer, hypertension and/or a metabolic condition in a subject is also disclosed.
Influence of the chemical structure on odor qualities and odor thresholds in homologous series of alka-1,5-dien-3-ones, alk-1-en-3-ones, alka-1,5-dien-3-ols, and alk-1-en-3-ols
Lorber, Katja,Schieberle, Peter,Buettner, Andrea
, p. 1025 - 1031 (2014/03/21)
Odor qualities and odor thresholds in air in homologous series of synthesized alk-1-en-3-ols and alka-1,5-dien-3-ols and their corresponding ketones were evaluated by gas chromatography-olfactometry. In the series of the alk-1-en-3-ols and alk-1-en-3-ones the odor quality changed successively from pungent for the compounds with five carbon atoms via metallic, vegetable-like for the six- and seven-carbon odorants to mushroom-like for the compounds with eight and nine carbon atoms. With further increase in chain length the mushroom-like impression decreased and changed to citrus-like, soapy, or herb-like. In both series, two odor threshold minima were found for the six-carbon and also for the eight- and nine-carbon odorants, respectively. In contrast to this, the odor qualities in the series of the (Z)- and (E)-alka-1,5-dien-3-ols and their corresponding ketones did not change significantly with geranium-like, metallic odors and an increasing mushroom-like odor note with increasing chain length. The lowest thresholds were found for the eight- and nine-carbon (Z)-compounds, respectively.