1034343-24-2

Basic information

• Product Name: 4-O-benzyl-3,5-di-O-(methoxymethyl)gallic acid
• Synonyms: 4-O-benzyl-3,5-di-O-(methoxymethyl)gallic acid
• CAS NO: 1034343-24-2
• Molecular Weight: 348.353
• Mol File: 1034343-24-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-O-benzyl-3,5-di-O-(methoxymethyl)gallic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-O-benzyl-3,5-di-O-(methoxymethyl)gallic acid(1034343-24-2)
• EPA Substance Registry System: 4-O-benzyl-3,5-di-O-(methoxymethyl)gallic acid(1034343-24-2)

Safety Data

• Hazardous Substances Data: 1034343-24-2(Hazardous Substances Data)

Upstream product

• 91925-82-5 3,5-dihydroxy-4-(phenylmethoxy)benzoic acid methyl ester 
• 100-39-0 benzyl bromide 
• 99-24-1 methyl galloate 
• 1034343-25-3 methyl 4-O-benzyl-3,5-di-O-methoxymethylgallate 

Downstream Products

• 1034343-26-4 C₄₀H₄₆O₁₄ 
• 1034343-27-5 C₆₅H₇₀O₁₈ 
• 1431081-25-2 ethyl 2,3-di-O-benzyl-4,6-O-bis(4-O-benzyl-3,5-di-O-methoxymethylgalloyl)-1-thio-β-D-glucopyranoside 
• 1431081-29-6 ethyl 2,3-di-O-benzyl-4,6-O-bis(4-O-benzylgalloyl)-1-thio-β-D-glucopyranoside 

Relevant articles and documents

High-yield total synthesis of (-)-strictinin through intramolecular coupling of gallates

This paper describes a total synthesis of (-)-strictinin, an ellagitannin that is 1-O-galloyl-4,6-O-(S)-hexahydroxydiphenoyl (HHDP)-β-d-glucose. In the study, total efficiency of the synthesis was improved to produce a 78% overall yield in 13 steps from d-glucose. In the synthesis, formation of the 4,6-(S)-HHDP bridge including the 11-membered bislactone ring was a key step, in which intramolecular aryl-aryl coupling was adopted. The coupling was oxidatively induced by CuCl2-n-BuNH2 with perfect control of the axial chirality, and the reaction conditions of this coupling were optimized thoroughly to achieve the quantitative formation of the bridge.