10348-47-7 Usage
General Description
Ethyl 2-hydroxy-4-methylvalerate is a chemical compound with the molecular formula C8H16O3. It is primarily recognized for its use in the creation of various flavors and fragrances due to its fruity, apple-like aroma. This clear to yellow liquid has applications in food, beverages, cosmetics, and other consumer goods to add fruity or floral scents. It is also known as ethyl alpha-hydroxy-isovalerate and falls under the category of an ester, which are organic compounds produced by reacting an oxoacid with a hydroxyl compound such as alcohol or phenol.
Check Digit Verification of cas no
The CAS Registry Mumber 10348-47-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,3,4 and 8 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 10348-47:
(7*1)+(6*0)+(5*3)+(4*4)+(3*8)+(2*4)+(1*7)=77
77 % 10 = 7
So 10348-47-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H16O3/c1-4-11-8(10)7(9)5-6(2)3/h6-7,9H,4-5H2,1-3H3
10348-47-7Relevant articles and documents
Asymmetric Synthesis of N-Substituted α-Amino Esters from α-Ketoesters via Imine Reductase-Catalyzed Reductive Amination
Yao, Peiyuan,Marshall, James R.,Xu, Zefei,Lim, Jesmine,Charnock, Simon J.,Zhu, Dunming,Turner, Nicholas J.
supporting information, p. 8717 - 8721 (2021/03/16)
N-Substituted α-amino esters are widely used as chiral intermediates in a range of pharmaceuticals. Here we report the enantioselective biocatalyic synthesis of N-substituted α-amino esters through the direct reductive coupling of α-ketoesters and amines employing sequence diverse metagenomic imine reductases (IREDs). Both enantiomers of N-substituted α-amino esters were obtained with high conversion and excellent enantioselectivity under mild reaction conditions. In addition >20 different preparative scale transformations were performed highlighting the scalability of this system.
