103505-49-3

Basic information

• Product Name: 6-CHLORO-N4-(4-CHLOROPHENYL)-4,5-PYRIMIDINEDIAMINE
• Synonyms: 6-CHLORO-N4-(4-CHLOROPHENYL)-4,5-PYRIMIDINEDIAMINE;4-(4-Chlorophenyl)amino-5-amino-6-chloropyrimidine;6-Chloro-N4-(4-chloro-phenyl)-pyriMidine-4,5-diaMine;4,5-Pyrimidinediamine, 6-chloro-N4-(4-chlorophenyl)-
• CAS NO: 103505-49-3
• Molecular Formula: C₁₀H₈Cl₂N₄
• Molecular Weight: 255.1
• Mol File: 103505-49-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 395.618°C at 760 mmHg
• Flash Point: 193.063°C
• Appearance: /
• Density: 1.518g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.712
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-CHLORO-N4-(4-CHLOROPHENYL)-4,5-PYRIMIDINEDIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-N4-(4-CHLOROPHENYL)-4,5-PYRIMIDINEDIAMINE(103505-49-3)
• EPA Substance Registry System: 6-CHLORO-N4-(4-CHLOROPHENYL)-4,5-PYRIMIDINEDIAMINE(103505-49-3)

Safety Data

• Hazardous Substances Data: 103505-49-3(Hazardous Substances Data)

Usage

General Description

6-CHLORO-N4-(4-CHLOROPHENYL)-4,5-PYRIMIDINEDIAMINE is a chemical compound that belongs to the class of pyrimidine derivatives. It is a white to off-white powder that is used in pharmaceutical research and development. 6-CHLORO-N4-(4-CHLOROPHENYL)-4,5-PYRIMIDINEDIAMINE has potential biological activity and can be utilized for medicinal purposes, particularly in the treatment of various diseases. It has a molecular formula of C11H8Cl2N4 and a molecular weight of 256.11 g/mol. 6-CHLORO-N4-(4-CHLOROPHENYL)-4,5-PYRIMIDINEDIAMINE is a valuable chemical for scientific and medical research, and its properties make it a promising candidate for further investigation in drug discovery and development.

InChI:InChI=1/C10H8Cl2N4/c11-6-1-3-7(4-2-6)16-10-8(13)9(12)14-5-15-10/h1-5H,13H2,(H,14,15,16)

Upstream product

• 5413-85-4 5-amino-4,6-dichloropyridimine 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 103566-04-7 6-chloro-9-(p-chlorophenyl)-9H-purine 
• 686344-50-3 6-chloro-9-(4-chlorophenyl)-8-(2-chlorophenyl)-9H-purine 
• 1408075-34-2 1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-piperidin-4-amine 
• 1408075-33-1 tert-butyl N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}carbamate 
• 1307786-04-4 6-chloro-9-(4-chlorophenyl)-8-ethyl-9H-purine 
• 686344-49-0 9-(4-chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-ol 
• 686344-48-9 2-chloro-N-[4-chloro-6-(4-chlorophenylamino)pyrimidin-5-yl]benzamide 
• 875925-98-7 (4-chloro-phenyl)-(8-fluoro-5-oxa-2,4,11-triaza-dibenzo[a,d]cyclohepten-1-yl)-amine 
• 205753-24-8 7-Chloro-3-(4-chloro-phenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine 

Relevant articles and documents

Functionalized 6-(Piperidin-1-yl)-8,9-Diphenyl Purines as Peripherally Restricted Inverse Agonists of the CB1 Receptor

Peripherally restricted CB1 receptor antagonists may be useful in treating metabolic syndrome, diabetes, liver diseases, and gastrointestinal disorders. Clinical development of the centrally acting CB1 inverse agonist otenabant (1) was halted due to its p

A One-Pot Synthesis of Highly Functionalized Purines

Highly substituted purines were synthesized in good to high yields through a one-pot straightforward metal-free scalable method, using the Traube synthesis adapted to Vilsmeier-type reagents. From 5-amino-4-chloropyrimidines, new 9-aryl-substituted chloropurines and intermediates for peptide nucleic acid synthesis were prepared. Variant procedures allowing a rapid synthesis of ribonucleosides and 7-benzylpurine from 5-amidino-6-aminopyrimidines are also reported to illustrate the high potential of this versatile toolbox. This route appears to be particularly interesting in the field of nucleic acids for a direct and rapid access to various new 8-alkylpurine nucleosides.

ARYLPIPERAZINE-CONTAINING PURINE DERIVATIVES AND USES THEREOF

A novel arylpiperazine-containing purine derivatives and a pharmaceutical composition comprising the same as an active ingredient, which are useful for preventing or treating depressive disorders, are provided.