103526-92-7Relevant academic research and scientific papers
α-ALKYLATION OF ACYCLIC AMINO ACIDS WITH SELF-REPRODUCTION OF THE CENTER OF CHIRALITY. A NEW ROUTE TO (S)-(+)-α-ALKYLATED ASPARTIC ACIDS.
Fadel, Antoine,Salaun, Jacques
, p. 2243 - 2246 (1987)
The amino acids 1a-d (alanine, phenylalanine, valine and methionine) are alkylated by ethyl bromoacetate, with inversion of configuration, to provide readily with high stereoselectivity the α-alkylated aspartic acids 9a-d through the chiral enolates 7a-d
