1035261-11-0

Upstream product

• 772-59-8 (3-bromo-4-methoxyphenyl)-acetonitrile 
• 111-44-4 3-oxa-1,5-dichloropentane 
• 5414-19-7 1,1'-oxybis(2-bromo-ethane) 

Downstream Products

• 1035261-12-1 4-(3-bromo-4-methoxyphenyl)-tetrahydro-2H-pyran-4-carboxylic acid 
• 1159185-86-0 4-(4-methoxy-3-(4-(1-methyl-1H-pyrazol-5-yl)phenylthio)phenyl)tetrahydro-2H-pyran-4-carbonitrile 
• 1035261-13-2 diethyl 2-(4-(3-bromo-4-methoxyphenyl)-tetrahydro-2H-pyran-4-carbonyl)malonate 

Relevant academic research and scientific papers

PYRAZOLE DERIVATIVES AS 5-LO INHIBITORS

The invention relates to compounds of formula (I) processes for their preparation, their use as 5-lipoxygenase inhibitors and pharmaceutical compositions containing the same.

NAPHTHALENONE COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF

Compounds of Formula (I) and Formula (II) are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula(I) and Formula (II) have the following structures, where the definitions of the variables are provided herein.