772-59-8

Usage

Uses

Used in Pharmaceutical Industry:
3-Bromo-4-methoxyphenylacetonitrile is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of active pharmaceutical ingredients and medical drugs. Its unique chemical structure allows for the creation of various pharmaceutical formulations.
Used in Agrochemical Industry:
3-Bromo-4-methoxyphenylacetonitrile is used as an intermediate in the synthesis of agrochemicals, contributing to the development of effective compounds for agricultural applications.
Used in Chemical Industry:
3-Bromo-4-methoxyphenylacetonitrile is used as a building block for the synthesis of various organic compounds, showcasing its versatility and importance in the chemical industry. Its reactivity and chemical properties make it a valuable component in the creation of a wide array of organic substances.

InChI:InChI=1/C9H8BrNO/c1-12-9-3-2-7(4-5-11)6-8(9)10/h2-3,6H,4H2,1H3

Upstream product

• 701-94-0 3-bromo-4-methoxybenzyl chloride 
• 151-50-8 potassium cyanide 
• 34841-06-0 3-bromo-4-methoxybenzylaldehyde 
• 38493-59-3 (3-bromo-4-methoxy-phenyl)-methanol 
• 123-11-5 4-methoxy-benzaldehyde 
• 89978-72-3 2-bromo-4-(bromomethyl)-1-methoxybenzene 
• 143-33-9 sodium cyanide 
• 104-47-2 p-methoxybenzylnitrile 

Downstream Products

• 774-81-2 (3-bromo-4-methoxy-phenyl)-acetic acid 
• 33839-30-4 (3-ethyl-4-methoxyphenyl)acetonitrile 
• 31859-25-3 4-Methoxy-3-isopropylphenylacetonitrile 
• 1035261-11-0 4-(3-bromo-4-methoxyphenyl)-tetrahydro-2H-pyran-4-carbonitrile 
• 91348-43-5 2-(3-bromo-4-methoxyphenyl)-3-oxobutanenitrile 
• 777-64-0 2-(3-Bromo-4-methoxy-phenyl)-N-hydroxy-acetamidine 
• 628311-33-1 2-(3-bromo-4-methoxy-phenyl)-2-methyl-propionitrile 
• 1627110-80-8 ethyl 2-(5-bromo-4-methoxy-2-(perfluorohexyl)phenyl)-2-cyanoacetate 
• 73348-21-7 2-(3-bromo-4-hydroxyphenyl)acetonitrile 

Relevant academic research and scientific papers

Palladium-Catalyzed, ortho-Selective C-H Halogenation of Benzyl Nitriles, Aryl Weinreb Amides, and Anilides

A palladium-catalyzed, ortho-selective C-H halogenation methodology is reported herein. The highlight of the work is the highly selective C(sp2)-H functionalization of benzyl nitriles in the presence of activated C(sp3)-H bond, which results in good yields of the halogenated products with excellent regioselectivity. Along with benzyl nitriles, aryl Weinreb amides and anilides have been evaluated for the transformation using aprotic conditions. Mechanistic studies yield interesting aspects with respect to the pathway of the reaction and the directing group abilities.

PYRAZOLE DERIVATIVES AS 5-LO INHIBITORS

The invention relates to compounds of formula (I) processes for their preparation, their use as 5-lipoxygenase inhibitors and pharmaceutical compositions containing the same.