103539-19-1

Basic information

• Product Name: 2,4-dibromo-7-(2-hydroxyanilino)tropone
• Synonyms: 2,4-dibromo-7-(2-hydroxyanilino)tropone
• CAS NO: 103539-19-1
• Molecular Weight: 371.028
• Mol File: 103539-19-1.mol

Chemical Properties

• CAS DataBase Reference: 2,4-dibromo-7-(2-hydroxyanilino)tropone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dibromo-7-(2-hydroxyanilino)tropone(103539-19-1)
• EPA Substance Registry System: 2,4-dibromo-7-(2-hydroxyanilino)tropone(103539-19-1)

Safety Data

• Hazardous Substances Data: 103539-19-1(Hazardous Substances Data)

Upstream product

• 95-55-6 2-amino-phenol 
• 33662-35-0 2,4-dibromo-7-methoxycyclohepta-2,4,6-trien-1-one 

Downstream Products

• 103539-22-6 2,4-dibromo-7-(2-methoxyanilino)tropone 

Relevant articles and documents

Intermolecular Bromine Transfer of 2-Amino-7-bromotropone Derivatives Catalyzed by Strong Acid

Upon heating acetic acid containing a trace of concd sulfuric acid at 120 deg C under nitrogen, 2-bromo-7-(2-hydroxyanilino)tropone (1a) gave 6-bromocycloheptabenzoxazine (2a) as the main product and cycloheptabenzoxazine, its 6,8-dibromo derivative and trace amounts of other mono, di-, and tribromo compounds.This reaction became much more complex in the presence of oxygen.A similar bromine transfer was observed for 2-bromo-7-(dimethylamino)-, 7-(2-hydroxy-5-methylanilino)-, and 7-(2-methoxyanilino)tropone although the cite of the intermolecular bromine transfer depended upon the structures of the substrates and the reaction conditions.In contrast, 2a and 2-amino-5-bromotropone derivatives were completely stable towards the strong acid.Possible reaction pathways for this bromine transfer reaction are discussed.