1035808-45-7Relevant academic research and scientific papers
A concise synthesis of the ab-ring fragment of (-)-gambierol
Fuwa, Haruhiko,Hirota, Kazuaki,Sasaki, Makoto
, p. 127 - 132 (2012)
We describe herein a concise synthesis of the AB-ring fragment of gambierol, wherein silver(I) trifluoromethanesulfonate-catalyzed 6-endo cyclization of a hydroxy ynone was exploited for the formation of the A-ring.
Pd-catalyzed domino synthesis of internal alkynes using triarylbismuths as multicoupling organometallic nucleophiles
Rao, Maddali L. N.,Jadhav, Deepak N.,Dasgupta, Priyabrata
supporting information; experimental part, p. 2048 - 2051 (2010/07/03)
Figure presented The domino coupling reaction of 1,1-dibromo-1-alkenes with triarylbismuth nucleophiles has been demonstrated to furnish disubstituted alkynes directly under catalytic palladium conditions. The couplings of triarylbismuths as multicoupling nucleophiles with 3 equiv of 1,1-dibromo-1-alkenes are very fast, affording high yields of alkynes in a short reaction time. Thus, an efficient domino process has been accomplished using 1,1-dibromo-1-alkenes as surrogates for internal alkyne synthesis in couplings with triarylbismuths in a one-pot operation.
