1036278-66-6

Basic information

• Product Name: dimethyl (S)-4-(tert-butyldiphenylsilyloxy)-3-methylbutane-1,1-dicarboxylate
• Synonyms: dimethyl (S)-4-(tert-butyldiphenylsilyloxy)-3-methylbutane-1,1-dicarboxylate
• CAS NO: 1036278-66-6
• Molecular Weight: 442.627
• Mol File: 1036278-66-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: dimethyl (S)-4-(tert-butyldiphenylsilyloxy)-3-methylbutane-1,1-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl (S)-4-(tert-butyldiphenylsilyloxy)-3-methylbutane-1,1-dicarboxylate(1036278-66-6)
• EPA Substance Registry System: dimethyl (S)-4-(tert-butyldiphenylsilyloxy)-3-methylbutane-1,1-dicarboxylate(1036278-66-6)

Safety Data

• Hazardous Substances Data: 1036278-66-6(Hazardous Substances Data)

Upstream product

• 123444-67-7 (R)-3-[(tert-butyl)diphenylsilyloxy]-1-iodo-2-methylpropane 
• 108-59-8 malonic acid dimethyl ester 
• 105859-46-9 (2R)-(tert-butyldimethyl)-(3-iodo-2-methylpropoxy)silane 

Downstream Products

• 1036278-68-8 C₂₃H₃₄O₃Si 
• 371784-89-3 (S)-5-(tert-butyldiphenylsilyloxy)-4-methyl-pentanol 

Relevant articles and documents

The first enantioselective synthesis of palinurin

The first enantioselective synthesis of palinurin has been accomplished starting from commercially available furaldehyde and (R)-methyl-3-hydroxy-2- methylpropionate; the key steps of the synthesis include the use of a chiral pyrrolidine to create the chiral tetronic moiety, and Horner-Wadsworth-Emmons, Wittig and Wittig-Horner reactions to construct the alkene units.