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1036334-65-2

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1036334-65-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1036334-65-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,6,3,3 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1036334-65:
(9*1)+(8*0)+(7*3)+(6*6)+(5*3)+(4*3)+(3*4)+(2*6)+(1*5)=122
122 % 10 = 2
So 1036334-65-2 is a valid CAS Registry Number.

1036334-65-2Downstream Products

1036334-65-2Relevant articles and documents

Pyridyl-phenyl ether monoamine reuptake inhibitors: Impact of lipophilicity on dual SNRI pharmacology and off-target promiscuity

Whitlock, Gavin A.,Fish, Paul V.,Fray, M. Jonathan,Stobie, Alan,Wakenhut, Florian

, p. 2896 - 2899 (2008/12/22)

A novel series of pyridyl-phenyl ethers are disclosed, which possess dual 5-HT and NA reuptake pharmacology with good selectivity over dopamine reuptake inhibition. An analysis of the relationship between lipophilicity and pharmacology highlighted that potent dual SNRI activity was only achievable at c log P > 3.5. The series was found to possess significant polypharmacology issues, and we concluded that this off-target promiscuity was related to lipophilicity.

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