1036715-69-1

Upstream product

• 640734-60-7 3-azido-1-(4-methoxy-phenyl)-propan-1-one 
• 58503-60-9 3-azidopropanal 
• 696-62-8 para-iodoanisole 
• 33994-11-5 α-Bromoethyl p-methoxaphenyl ketone 
• 100-66-3 methoxybenzene 

Downstream Products

• 1036715-74-8 (S)-3-azido-1-(4-methoxyphenyl)propan-1-ol 
• 1036715-79-3 (R)-3-azido-1-(4-methoxyphenyl)propyl acetate 
• 1467719-98-7 3-isothiocyanato-1-(4-methoxyphenyl)propan-1-ol 
• 1467719-99-8 1-{3-hydroxy-3-(4-methoxyphenyl)propyl}-3-methylthiourea 
• 1467720-00-8 1-{3-hydroxy-3-(4-methoxyphenyl)propyl}-3-isopropylthiourea 
• 1467720-01-9 1-{3-hydroxy-3-(4-methoxyphenyl)propyl}-3-phenylthiourea 

Relevant academic research and scientific papers

Novel compound capable of activating Nrf2, and pharmaceutical compositions comprising the same

The present invention provides a novel compound which can activate Nrf2 that is a transcription factor for expression of the quinone reductase gene. Therefore the compound is effective for inhibiting apoptosis and preventing and treating brain nerve disea

Electronic and steric effects on the intramolecular Schmidt reaction of alkyl azides with secondary benzyl alcohols

The intramolecular Schmidt reaction of simple azido secondary benzyl alcohols has been realized for the first time. Investigation of the electronic and steric effects of the substrates on the product outcome was conducted. Unique intramolecular Schmidt rearrangements were observed with the formation of a cinnamaldehyde derivative and aryl aldehydes, respectively. Using this protocol, an efficient synthesis of dihydrobenzotriazine derivatives was achieved. Moreover, a practical approach to 2-aryl-1-pyrrolines was also accessed.

Synthesis and Nrf2 activating ability of thiourea and vinyl sulfoxide derivatives

Thiourea and vinyl sulfoxide derivatives were designed based on the structures of sulforaphane and gallic acid, prepared and tested for HO-1 inducing activity as a measure of Nrf2 activation, and inhibitory effect on NO production as a measure of anti-inf

Synthesis of enantiomerically pure γ-azidoalcohols by lipase-catalyzed transesterification

An enantioselective synthesis of chiral γ-azidoalcohols via lipase-catalyzed resolution is described. The efficiency of various lipases and the effect of different solvents have been studied. Pseudomonas cepacia immobilized on diatomaceous earth (PS-D) in n-hexane catalyzed the transesterification process in an efficient manner providing γ-azidoalcohols in high enantiomeric excess.