1467720-01-9Relevant academic research and scientific papers
Novel compound capable of activating Nrf2, and pharmaceutical compositions comprising the same
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Paragraph 1069; 1101-1103, (2016/10/08)
The present invention provides a novel compound which can activate Nrf2 that is a transcription factor for expression of the quinone reductase gene. Therefore the compound is effective for inhibiting apoptosis and preventing and treating brain nerve disea
Synthesis and Nrf2 activating ability of thiourea and vinyl sulfoxide derivatives
Shim, Young Sun,Hwang, Hyun Sook,Nam, Ghilsoo,Choi, Kyung Il
supporting information, p. 2317 - 2320 (2013/09/24)
Thiourea and vinyl sulfoxide derivatives were designed based on the structures of sulforaphane and gallic acid, prepared and tested for HO-1 inducing activity as a measure of Nrf2 activation, and inhibitory effect on NO production as a measure of anti-inf
