103861-77-4

Basic information

• Product Name: 2-(3-METHOXYPHENYL)PYRROLIDINE
• Synonyms: CHEMBRDG-BB 4002379;2-(3-METHOXYPHENYL)PYRROLIDINE;AKOS BB-8862;2-(3-methoxyphenyl)pyrrolidine(SALTDATA: FREE);Pyrrolidine,2-(3-Methoxyphenyl)-
• CAS NO: 103861-77-4
• Molecular Formula: C₁₁H₁₅NO
• Molecular Weight: 177.24
• Product Categories: pharmacetical
• Mol File: 103861-77-4.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 280℃
• Flash Point: 111℃
• Appearance: /
• Density: 1.024
• Vapor Pressure: 0.00398mmHg at 25°C
• Refractive Index: 1.524
• Storage Temp.: 2-8°C(protect from light)
• PKA: 9.94±0.10(Predicted)
• CAS DataBase Reference: 2-(3-METHOXYPHENYL)PYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-METHOXYPHENYL)PYRROLIDINE(103861-77-4)
• EPA Substance Registry System: 2-(3-METHOXYPHENYL)PYRROLIDINE(103861-77-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• WGK Germany: 3
• Hazardous Substances Data: 103861-77-4(Hazardous Substances Data)

Usage

General Description

2-(3-Methoxyphenyl)pyrrolidine is a chemical compound often used in the field of organic chemistry and pharmaceutical chemistry. It's known for its structures of pyrrolidine, a heterocyclic amine, and a methoxyphenyl group, providing applications in the synthesis of complex molecules. It can be used as a chemical intermediate in the development of various drugs and bioactive compounds. However, it should be handled with care, as it can be harmful upon exposure, ingestion, or inhalation, similar to many other chemicals. Details about its toxicity and environmental effects are limited and further investigation is required.

InChI:InChI=1/C11H15NO/c1-13-10-5-2-4-9(8-10)11-6-3-7-12-11/h2,4-5,8,11-12H,3,6-7H2,1H3

Upstream product

• 104174-43-8 4-(3-methoxyphenyl)butan-1-ol 
• 914954-34-0 tert-butyl (4-(3-methoxyphenyl)-4-oxobutyl)carbamate 
• 158819-49-9 5-(3-methoxyphenyl)pyrrolidin-2-one 
• 591-31-1 3-methoxy-benzaldehyde 
• 5264-35-7 2-methoxy-1-pyrroline 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 38102-72-6 4-oxo-4-(3-methoxyphenyl)butanenitrile 
• 71291-54-8 2-(3-anisyl)-Δ¹-pyrroline 
• 586-38-9 3-Methoxybenzoic acid 
• 10259-22-0 ethyl 3-methoxybenzoate 
• 2398-37-0 3-methoxyphenyl bromide 

Downstream Products

• 158819-53-5 1-Cyclopropylmethyl-2-(3-methoxyphenyl)pyrrolidine salicylate 
• 158819-77-3 2-{2-[2-(3-methoxyphenyl)-1-pyrrolidinyl]ethyl}-1H-isoindole-1,3(2H)dione 
• 917904-19-9 2-(4-bromo-phenyl)-2-hydroxy-1-[2-(3-methoxy-phenyl)-pyrrolidin-1-yl]-ethanone 
• 917904-17-7 2-hydroxy-1-[2-(3-methoxy-phenyl)-pyrrolidin-1-yl]-2-(4-methylsulfanyl-phenyl)-ethanone 

Relevant articles and documents

O-benzoylhydroxylamines as alkyl nitrene precursors: Synthesis of saturated N-heterocycles from primary amines

We introduce O-benzoylhydroxylamines as competent alkyl nitrene precursors. The combination of readily available, stable substrates and a proficient rhodium catalyst provides a straightforward means for the construction of various pyrrolidine rings from the corresponding primary amines. Preliminary mechanistic investigation suggests that the structure of the nitrene precursor plays a role in determining the nature of the resulting reactive intermediate.

PYRROLIDINE GLYCOSIDASE INHIBITORS

Compounds of formula (I) wherein A, W, R3b, Z and p have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.

SUBSTITUTED N-ARYLPYRROLIDINES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS

The present invention provides a compound of the formula: Formula I or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of Formula I in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly frailty, osteoporosis, osteopenia, and male and female sexual dysfunction comprising administering to a patient in need thereof an effective amount of a compound of Formula I.