914954-34-0

Basic information

• Product Name: tert-butyl (4-(3-methoxyphenyl)-4-oxobutyl)carbamate
• Synonyms: tert-butyl (4-(3-methoxyphenyl)-4-oxobutyl)carbamate
• CAS NO: 914954-34-0
• Molecular Weight: 293.363
• Mol File: 914954-34-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: tert-butyl (4-(3-methoxyphenyl)-4-oxobutyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (4-(3-methoxyphenyl)-4-oxobutyl)carbamate(914954-34-0)
• EPA Substance Registry System: tert-butyl (4-(3-methoxyphenyl)-4-oxobutyl)carbamate(914954-34-0)

Safety Data

• Hazardous Substances Data: 914954-34-0(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 2398-37-0 3-methoxyphenyl bromide 
• 85909-08-6 tert-butyl 2-oxopyrrolidine-1-carboxylate 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 

Downstream Products

• 1228556-79-3 (+)-2-(3-methoxyphenyl)pyrrolidine 
• 1228556-79-3 (–)-2-(3-methoxyphenyl)pyrrolidine 
• 914954-43-1 2-(3-methoxy-phenyl)-2-methyl-pyrrolidine 
• 103861-77-4 2-(3-methoxyphenyl)pyrrolidine 
• 71291-54-8 2-(3-anisyl)-Δ¹-pyrroline 

Relevant articles and documents

PYRROLIDINE GLYCOSIDASE INHIBITORS

Compounds of formula (I) wherein A, W, R3b, Z and p have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.

Enantioselective Direct Synthesis of Free Cyclic Amines via Intramolecular Reductive Amination

Chiral cyclic amines can be prepared via intramolecular reductive amination of N-Boc-protected amino ketones in a one-pot process. With the complex of iridium and f-spiroPhos as the catalyst, a range of N-Boc-protected amino ketones are smoothly transformed into chiral cyclic free amines in high yields and excellent enantioselectivities (up to 97% ee). Moreover, this method can also be successfully applied to the synthesis of a κ-opioid receptor selective antagonist, (S)-1.