103901-74-2

Upstream product

• 81-20-9 2,6-dimethylnitrobenzene 
• 3096-63-7 N-(2,6-dimethylphenyl)hydroxylamine 
• 75-36-5 acetyl chloride 

Downstream Products

• 103901-77-5 N-{6-[(E)-Acetylimino]-1,5-dimethyl-cyclohexa-2,4-dienyl}-2,2,2-trichloro-N-methyl-acetamide 
• 113831-48-4 N-((3R,3aR,7aR)-3-Benzenesulfonyl-4,7a-dimethyl-2-oxo-1,2,3,7a-tetrahydro-inden-3a-yl)-acetamide 
• 113831-51-9 N-((1R,3aS,7aS)-1-Benzenesulfonyl-1,3a,5-trimethyl-2-oxo-2,3,3a,7a-tetrahydro-1H-inden-4-yl)-acetamide 
• 113831-47-3 N-[(3R,3aR,7aR)-3-(Diphenyl-phosphinoyl)-4,7a-dimethyl-2-oxo-1,2,3,7a-tetrahydro-inden-3a-yl]-acetamide 
• 103901-78-6 N-{6-[(E)-Acetylimino]-1,5-dimethyl-cyclohexa-2,4-dienyl}-N-methyl-4-nitro-benzamide 
• 6337-56-0 N-(4-hydroxy-2,6-dimethylphenyl)acetamide 

Relevant academic research and scientific papers

Redox-Neutral Selenium-Catalysed Isomerisation of para-Hydroxamic Acids into para-Aminophenols

A selenium-catalysed para-hydroxylation of N-aryl-hydroxamic acids is reported. Mechanistically, the reaction comprises an N?O bond cleavage and consecutive selenium-induced [2,3]-rearrangement to deliver para-hydroxyaniline derivatives. The mechanism is studied through both 18O-crossover experiments as well as quantum chemical calculations. This redox-neutral transformation provides an unconventional synthetic approach to para-aminophenols.