103956-00-9

Basic information

• Product Name: METHYL 6-AMINO-4-INDOLECARBOXYLATE
• Synonyms: 6-AMINO-4-INDOLECARBOXYLIC ACID METHYL ESTER;6-AMINO-1H-INDOLE-4-CARBOXYLIC ACID METHYL ESTER;METHYL 6-AMINO-4-INDOLECARBOXYLATE;1H-Indole-4-carboxylicacid,6-amino-,methylester(9CI);Methyl 6-Amino-4-indolecarboxylate Hydrochloride;6-AMINOINDOLE-4-CARBOXYLIC ACID METHYL ESTER;Methyl 6-aminoindole-4-carboxylate;Methyl 6-aMino-1H-indole-4-carboxylate
• CAS NO: 103956-00-9
• Molecular Formula: C₁₀H₁₀N₂O₂
• Molecular Weight: 190.2
• Product Categories: AMINOACID;Amines and Anilines;Heterocycles;pharmacetical
• Mol File: 103956-00-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 429.8 °C at 760 mmHg
• Flash Point: 213.7 °C
• Appearance: /
• Density: 1.339
• Vapor Pressure: 1.36E-07mmHg at 25°C
• Refractive Index: 1.694
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 17.03±0.30(Predicted)
• CAS DataBase Reference: METHYL 6-AMINO-4-INDOLECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 6-AMINO-4-INDOLECARBOXYLATE(103956-00-9)
• EPA Substance Registry System: METHYL 6-AMINO-4-INDOLECARBOXYLATE(103956-00-9)

Safety Data

• Hazardous Substances Data: 103956-00-9(Hazardous Substances Data)

Usage

General Description

Methyl 6-amino-4-indolecarboxylate is a chemical compound that belongs to the class of indolecarboxylates. It is composed of a methyl group, an amino group, and a carboxylate group attached to a 6-amino-4-indole nucleus. Methyl 6-amino-4-indolecarboxylate is commonly used as an intermediate in the synthesis of pharmaceuticals and organic compounds. It has been studied for its potential biological activities and has been found to possess certain pharmacological properties. Methyl 6-amino-4-indolecarboxylate is an important building block in the field of medicinal chemistry and has potential applications in the development of new drugs and drug discovery research.

InChI:InChI=1/C10H10N2O2/c1-14-10(13)8-4-6(11)5-9-7(8)2-3-12-9/h2-5,12H,11H2,1H3

Upstream product

• 52090-24-1 methyl 2-methyl-3,5-dinitrobenzoate 
• 28169-46-2 3,5-dinitro-o-toluic acid 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 632627-91-9 6-{2-[5-chloro-2-(benzyloxy)phenyl]-5-methyl-pyrrol-1-yl}-1H-indole-4-carboxylic acid methyl ester 
• 948015-63-2 6-((tert-butoxycarbonyl)amino)-1H-indole-4-carboxylic acid 
• 731810-56-3 methyl 6-((tert-butoxycarbonyl)amino)-1H-indole-4-carboxylate 
• 632625-06-0 3-{2-[5-chloro-2-(benzyloxy)phenyl]-5-methyl-pyrrol-1-yl}-5-methanesulfonylaminobenzoic acid 
• 927427-94-9 C₁₇H₁₆N₂O₄S 

Relevant articles and documents

5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES

The invention is directed to substituted salicylamide derivatives. Specifically, the invention is directed to compounds according to Formula (I): wherein R, R1 and R2 are as defined herein, or a pharmaceutically acceptable salt thereof. The compounds of the invention are inhibitors of CD73 and can be useful in the treatment of cancer, pre-cancerous syndromes and diseases associated with CD73 inhibition, such as AIDS, the treatment of HIV, autoimmune diseases, infections, atherosclerosis, and ischemia–reperfusion injury. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting CD73 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

DIAZEPINOINDOLE DERIVATIVES AS KINASE INHIBITORS

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