1040232-97-0Relevant academic research and scientific papers
Organocatalytic asymmetric direct Michael addition of aromatic ketones to alkylidenemalononitriles
Yue, Lei,Du, Wei,Liu, Yan-Kai,Chen, Ying-Chun
, p. 3881 - 3884 (2008)
The asymmetric direct Michael addition of aromatic ketones to highly active alkylidenemalononitriles was investigated by employing a chiral primary amine 9-amino-9-deoxyepicinchonine. In general modest to good enantioselectivities (71-84% ee) could be obtained in acceptable isolated yields (48-85%) for an array of substrates.
