1040283-70-2Relevant academic research and scientific papers
N-hydroxypyrazolyl glycine derivatives as selective N-methyl-D-aspartic acid receptor ligands
Clausen, Rasmus P.,Christensen, Caspar,Hansen, Kasper B.,Greenwood, Jeremy R.,J?rgensen, Lars,Micale, Nicola,Madsen, Jens Christian,Nielsen, Birgitte,Egebjerg, Jan,Br?uner-Osborne, Hans,Traynelis, Stephen F.,Kristensen, Jesper L.
, p. 4179 - 4187 (2008)
A series of analogues based on N-hydroxypyrazole as a bioisostere for the distal carboxylate group of aspartate have been designed, synthesized, and pharmacologically characterized. Affinity studies on the major glutamate receptor subgroups show that thes
