104060-47-1

Basic information

• Product Name: L-Valine, N-[(phenylamino)carbonyl]-, methyl ester
• CAS NO: 104060-47-1
• Molecular Formula: C13H18N2O3
• Molecular Weight: 250.298
• Mol File: 104060-47-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: L-Valine, N-[(phenylamino)carbonyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Valine, N-[(phenylamino)carbonyl]-, methyl ester(104060-47-1)
• EPA Substance Registry System: L-Valine, N-[(phenylamino)carbonyl]-, methyl ester(104060-47-1)

Safety Data

• Hazardous Substances Data: 104060-47-1(Hazardous Substances Data)

Upstream product

• 4070-48-8 L-Valine methyl ester 
• 103-71-9 phenyl isocyanate 
• 6306-52-1 L-valine methylester hydrochloride 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 62-53-3 aniline 
• 72-18-4 L-valine 

Downstream Products

• 1294004-78-6 C₃₄H₄₂N₄O₈ 
• 223600-52-0 1-((S)-1-hydroxymethyl-2-methyl-propyl)-3-phenyl-urea 
• 84860-35-5 (S)-(phenylcarbamoyl)-N-valine 
• 65462-94-4 (S)-5-isopropyl-3-phenylimidazolidine-2,4-dione 
• 1412837-73-0 (S)-5-isopropyl-3-phenyl-1-propionylhydantoin 
• 1412838-10-8 (5S,2'R,3'S)-5-isopropyl-3-phenyl-1-[2'-methyl-3'-(p-methoxyphenylamino)-3'-phenylpropionyl]hydantoin 
• 1412838-16-4 (5S,2'R,3'S)-5-isopropyl-3-phenyl-1-[2'-methyl-3'-(p-methoxyphenylamino)-3'-(p-chlorophenyl)propionyl]hydantoin 
• 1412838-22-2 (5S,2'R,3'S)-5-isopropyl-3-phenyl-1-[2'-methyl-3'-(p-methoxyphenylamino)-3'-(m-nitrophenyl)propionyl]hydantoin 
• 1412838-34-6 (5S,2'R,3'S)-5-isopropyl-3-phenyl-1-[2'-methyl-3'-(p-methoxyphenylamino)-3'-(2''-furyl)propionyl]hydantoin 
• 1412838-40-4 (5S,2'R,3'S)-5-isopropyl-3-phenyl-1-[2'-methyl-3'-(p-methoxyphenylamino)-3'-(2''-thienyl)propionyl]hydantoin 
• 1412838-28-8 (5S,2'R,3'S)-5-isopropyl-3-phenyl-1-[2'-methyl-3'-(p-methoxyphenylamino)-3'-(2'',3''-methoxyphenyl)propionyl]hydantoin 

Relevant articles and documents

Asymmetric and diastereoselective Mannich reactions using hydantoin as a chiral auxiliary

The Mannich reaction of titanium enolates of a chiral hydantoin with various aldimines smoothly occurred in good yields and with high anti-diastereoselectivity. The Mannich adducts can be readily cleaved by alcoholysis to afford several β-amino ester derivatives in good yields and in almost enantiomerically pure form.

Solvent-free synthesis of novel chiral unsymmetrical urea molecular tweezers under microwave irradiation

Seven novel chiral unsymmetrical urea molecular tweezers based on 1, 3-phenoxyacetic acid have been designed and synthesised using solid K 2CO3 as supporter in the solvent-free conditions under microwave irradiation. This method is simple, fast, efficient and eco-friendly. The structures of target compounds were characterised by IR, 1H NMR, MS spectra and elemental analyses and their molecular recognition properties were investigated by UV-Vis spectral titration. The preliminary results indicated that these molecular tweezers possess good selectivity for D/L amino acid methyl esters and some anions.