104069-09-2

Basic information

• Product Name: 2-Cyclopenten-1-ol, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (1S,4R)-
• CAS NO: 104069-09-2
• Molecular Formula: C11H22O2Si
• Molecular Weight: 214.38
• Mol File: 104069-09-2.mol

Chemical Properties

• CAS DataBase Reference: 2-Cyclopenten-1-ol, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (1S,4R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclopenten-1-ol, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (1S,4R)-(104069-09-2)
• EPA Substance Registry System: 2-Cyclopenten-1-ol, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (1S,4R)-(104069-09-2)

Safety Data

• Hazardous Substances Data: 104069-09-2(Hazardous Substances Data)

Upstream product

• 1589-82-8 phenylmagnesium bromide 

Downstream Products

• 136176-21-1 tert-Butyl-[(3aR,4S,5R,6aS)-2-ethoxy-4-((E)-styryl)-hexahydro-cyclopenta[b]furan-5-yloxy]-dimethyl-silane 
• 136176-22-2 [(3aR,4R,5R,6aS)-4-((E)-2-Benzenesulfonyl-vinyl)-2-ethoxy-hexahydro-cyclopenta[b]furan-5-yloxy]-tert-butyl-dimethyl-silane 
• 61305-30-4 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (1S,4R)-4-(tert-butyl-dimethyl-silanyloxy)-cyclopent-2-enyl ester 
• 59995-47-0 (S)-4-hydroxycyclopent-2-en-1-one 
• 59995-47-0 (R)-(+)-4-hydroxy-2-cyclopentenone 
• 59995-48-1 (R)-4-acetoxycyclopent-2-en-1-one 
• 76822-56-5 mexiprostil 
• 1345817-43-7 C₂₇H₄₄O₃Si 
• 1345817-44-8 (1R,2S)-2-((S,E)-3-((benzyloxy)methoxy)oct-1-en-1-yl)cyclopent-3-enol 
• 1345817-45-9 (((((S,E)-1-((1S,5R)-5-(benzyloxy)cyclopent-2-en-1-yl)oct-1-en-3-yl)oxy)methoxy)methyl)benzene 
• 60176-77-4 (1S,4R)-4-hydroxy-2-cyclopentenyl acetate 

Relevant articles and documents

Synthesis of the active form of loxoprofen by using allylic substitutions in two steps

High regioselectivity for allylic substitution of the cyclopentenyl picolinate 5 with benzylcopper reagent was attained with ZnBr2, and the finding was applied to the p-BrC6H4CH2 reagent. The cyclopentene moiety in the product was reduced to the cyclopentane, and the p-BrC6H4 was converted to the "Cu"C6H4 for the second allylic substitution with picolinate 8 to furnish the title compound after oxidative cleavage of the resulting olefin moiety.