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104093-04-1

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104093-04-1 Usage

Derivative of coumarin

umbelliferone acetic acid
Commonly found in plants such as citrus fruits
Antioxidant and anti-inflammatory properties

Potential therapeutic effects

ability to inhibit the growth of certain types of cancer cells and potential use as a treatment for diabetes and other metabolic disorders
Used in the development of novel pharmaceutical drugs due to its interesting pharmacological properties.

Check Digit Verification of cas no

The CAS Registry Mumber 104093-04-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,0,9 and 3 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 104093-04:
(8*1)+(7*0)+(6*4)+(5*0)+(4*9)+(3*3)+(2*0)+(1*4)=81
81 % 10 = 1
So 104093-04-1 is a valid CAS Registry Number.

104093-04-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(7-hydroxy-2-oxochromen-3-yl)acetic acid

1.2 Other means of identification

Product number -
Other names 2H-1-Benzopyran-3-acetic acid,7-hydroxy-2-oxo

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:104093-04-1 SDS

104093-04-1Downstream Products

104093-04-1Relevant articles and documents

PSORALEN DERIVATIVES AS NON-PEPTIDIC INHIBITORS OF CHYMOTRYPSIN-LIKE ACTIVITY OF THE IMMUNOPROTEASOME

-

Paragraph 0083; 0084; 0085; 0086, (2016/10/11)

This invention relates to new inhibitors of chymothrypsin-like activity of the immunoproteasome (inhibitors of β5? or LMP7 subunit) with the general formula (I), where substituents are described in patent description. Compounds can be in the form of pure enantiomers or as racemic mixtures, or in the form of pharmaceutically acceptable salts. The present invention relates to the use of these inhibitors for the treatment of diseases where immunoproteasome activity is increased.

Microwave assisted one pot synthesis of 7-substituted 2-(2-oxo-2H-chromen-3-yl)acetic acids as precursors of new anti-tumour compounds

Kovacova, Silvia,Kovacikova, Lucia,Lacova, Margita,Bohac, Andrej,Salisova, Marta

, p. 806 - 811 (2011/11/06)

Perkin condensation with subsequent intramolecular lactonisation as one pot syntheses of 2-(2-oxo-2H-chromen-3-yl)acetic acids VIIa-Xa has been studied. The required acids VIIa-Xa were prepared as precursors of recently discovered compounds possessing antineoplastic activities. Syntheses of VIIa-Xa were carried out using para substituted 2-hydroxybenzaldehydes II-VI, succinic acid anhydride, sodium succinate under thermal or microwave conditions. Significant shortening of the reaction time under microwave irradiation was observed (18-50 min instead of 1.5-5 h of heating). Microwave assisted reactions proceeded more smoothly to give higher yield of the required products VIIa-Xa (31-61 %) compared to those under classical thermal conditions e.g. 21.8 % for IXa (Hurenkamp et al., 2007). Seven reaction by-products were isolated and determined as 2H,2′H-3,3′-bichromene-2,2′-diones VIIb-Xb and (E)-3-(2-hydroxystyryl)-2H-chromen-2-ones VIIc-IXc.

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