104102-98-9

Upstream product

• 700-38-9 2-nitro-5-methylphenol 
• 100-39-0 benzyl bromide 

Downstream Products

• 106877-38-7 5-methyl-2-(trifluoromethyl)phenol 
• 220985-65-9 N-(2,4-dimethoxy)-phenyl-2-benzyloxy-4-methylaniline 
• 220985-64-8 1-benzyloxy-3-methyl-9-H-carbazole 
• 220985-62-6 N-phenyl-2-benzyloxy-4-methylaniline 
• 14960-81-7 1-hydroxy-3-methyl-9H-carbazole 
• 220985-61-5 2-(benzyloxy)-4-methylaniline 

Relevant academic research and scientific papers

The first synthesis of optically pure biscarbazoles and determination of their absolute configurations

Optically pure dimeric O-demethylmurrayafoline A (1) and its 6,6'- dimethoxyl analog 2 were synthesized via the resolution of their corresponding camphorsulfonates of the racemates. The absolute configurations of (+)-1, (+)-2 and (-)-1, (-)-2 were assigne

INDOLINE DERIVATIVES

Compounds of Formula (I) are disclosed and methods of treating viral infections with compositions comprising such compounds.

Synthesis of optically pure Clausenamine-A and its demethoxylated analogs

The first total synthesis of Clausenamine-A (3) was developed involving the Suzuki cross-coupling and oxidative coupling reaction. The synthesis of its demethoxylated analogs 1 and 2 were also reported. Resolution of (+)-1, (+)-2, (+)-3 and (-)-1, (-)-2, (-)-3 were performed via their corresponding camphorsulfonates of the racemates. The absolute configurations of (+)-1, (+)-2, (+)-3 and (-)-1, (-)-2, (-)-3 were assigned as (aR) and (aS), respectively, by X-ray analysis and their CD spectrum. The primarily cytotoxic activities of these biscarbazoles against Plasmodium falciparum were briefly described. (C) 2000 Elsevier Science Ltd.