220985-65-9

Basic information

• Product Name: N-(2,4-dimethoxy)-phenyl-2-benzyloxy-4-methylaniline
• Synonyms: N-(2,4-dimethoxy)-phenyl-2-benzyloxy-4-methylaniline
• CAS NO: 220985-65-9
• Molecular Weight: 349.43
• Mol File: 220985-65-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2,4-dimethoxy)-phenyl-2-benzyloxy-4-methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,4-dimethoxy)-phenyl-2-benzyloxy-4-methylaniline(220985-65-9)
• EPA Substance Registry System: N-(2,4-dimethoxy)-phenyl-2-benzyloxy-4-methylaniline(220985-65-9)

Safety Data

• Hazardous Substances Data: 220985-65-9(Hazardous Substances Data)

Upstream product

• 20469-63-0 1-iodo-2,4-dimethoxybenzene 
• 220985-61-5 2-(benzyloxy)-4-methylaniline 
• 100-39-0 benzyl bromide 
• 104102-98-9 2-(benzyloxy)-4-methyl-1-nitrobenzene 
• 700-38-9 2-nitro-5-methylphenol 

Relevant articles and documents

Synthesis of optically pure Clausenamine-A and its demethoxylated analogs

The first total synthesis of Clausenamine-A (3) was developed involving the Suzuki cross-coupling and oxidative coupling reaction. The synthesis of its demethoxylated analogs 1 and 2 were also reported. Resolution of (+)-1, (+)-2, (+)-3 and (-)-1, (-)-2, (-)-3 were performed via their corresponding camphorsulfonates of the racemates. The absolute configurations of (+)-1, (+)-2, (+)-3 and (-)-1, (-)-2, (-)-3 were assigned as (aR) and (aS), respectively, by X-ray analysis and their CD spectrum. The primarily cytotoxic activities of these biscarbazoles against Plasmodium falciparum were briefly described. (C) 2000 Elsevier Science Ltd.