1041861-59-9Relevant articles and documents
Cooperative Metal-Ligand Catalyzed Intramolecular Hydroamination and Hydroalkoxylation of Allenes Using a Stable Iron Catalyst
El-Sepelgy, Osama,Brzozowska, Aleksandra,Sklyaruk, Jan,Jang, Yoon Kyung,Zubar, Viktoriia,Rueping, Magnus
supporting information, p. 696 - 699 (2018/02/09)
A new iron-catalyzed chemoselective intramolecular hydroamination and hydroalkoxylation of the readily available α-allenic amines and alcohols to valuable unsaturated 5-membered heterocycles, 2,3-dihydropyrrole and 2,3-dihydrofuran, is reported. Effective
A dramatic switch of enantioselectivity in asymmetric heck reaction by benzylic substituents of ligands
Wu, Wen-Qiong,Peng, Qian,Dong, Da-Xuan,Hou, Xue-Long,Wu, Yun-Dong
experimental part, p. 9717 - 9725 (2009/02/04)
A series of benzylic substituted P,N-ligands 1 and 2 have been synthesized. The Pd-complexes of these ligands show high catalytic activity and enantioselectivity in catalyzing the asymmetric Heck reaction. A dramatic switch in enantioselectivity is realized using ligands with and without substituents at the benzylic position of the ligand. Ligands 1 with H as the substituents offer products in (R)-configuration while ligands 2 with the methyl as substituents result in (S)-configuration products. In most cases high enantioselectivities are achieved. Density functional theory calculations on the reaction mechanism as well as X-ray analysis of 1a-PdCl2 and 2a-PdCl2 complexes provide a rational explanation for the above observations.
