1041934-93-3Relevant academic research and scientific papers
The use of fluoride as a leaving group: SN2′ displacement of a C-F bond on 3,3-difluoropropenes with organolithium reagents to give direct access to monofluoroalkenes
Bergeron, Maxime,Johnson, Thomas,Paquin, Jean-Francois
supporting information; experimental part, p. 11112 - 11116 (2012/02/02)
Lithium is the key to activate the nucleofuge ability of fluoride in the title transformation (see scheme). This simple and straightforward approach not only provides a practical synthetic method for the preparation of monofluoroalkenes, an important fluo
New methodology for the synthesis of α,α-difluoroketones
Biju, Purakkattle
, p. 1940 - 1945 (2008/09/20)
A new methodology is described for the synthesis of α,α- difluorinated ketones by the addition of organolithium reagents to α,α-difluoro-N-methoxy-N-methyl amides (Weinreb amides). Copyright Taylor & Francis Group, LLC.
