932-51-4

Usage

Uses

Used in Organic Synthesis:
2,5-DIMETHYLCYCLOHEXANONE is used as a building block in organic synthesis for various chemical reactions, contributing to the creation of a wide range of compounds and products.
Used in the Food Industry:
In the food industry, 2,5-DIMETHYLCYCLOHEXANONE is utilized as a flavoring agent, enhancing the taste and aroma of various food products.
Used in the Perfume Industry:
2,5-DIMETHYLCYCLOHEXANONE also serves as a fragrance in the perfume industry, adding to the complexity and appeal of scent compositions.
Used in Pharmaceutical Applications:
Due to its chemical reactivity, 2,5-DIMETHYLCYCLOHEXANONE has potential applications in pharmaceuticals, where it may be involved in the development of new drugs or medicinal compounds.
Used in Agrochemical Applications:
Similarly, in agrochemicals, 2,5-DIMETHYLCYCLOHEXANONE may be employed for the synthesis of various agrochemical products, contributing to advancements in crop protection and management.
Overall, 2,5-DIMETHYLCYCLOHEXANONE plays a significant role across multiple industries, from enhancing consumer products to contributing to the development of new chemical entities in pharmaceuticals and agrochemicals.

InChI:InChI=1S/C8H14O/c1-6-3-4-7(2)8(9)5-6/h6-7H,3-5H2,1-2H3

Upstream product

• 3809-32-3 2,5-dimethylcyclohexanol 
• 13368-65-5 (3R)-3-methylcyclohexanone 
• 64798-91-0 4-methyl-2-oxo-cyclohexanecarbaldehyde 
• 861538-31-0 1,4-dimethyl-cyclohexane-1,2-diol 
• 91056-56-3 2-acetyl-2,5-dimethyl-cyclohexanone 
• 861575-66-8 (1,2-dibromo-4-methyl-cyclohexyl)-acetic acid 
• 591-24-2 3-Methylcyclohexanone 
• 6610-21-5 6-methylcyclohex-2-en-1-one 
• 917-54-4 methyllithium 
• 7732-18-5 water 
• 95-87-4 2,5-Dimethylphenol 
• 67-56-1 methanol 
• 14845-35-3 2,5-dimethyl-cyclohex-2-enone 
• 97777-91-8 2-(4-methylcyclohex-1-en-1-yl)acetic acid 

Downstream Products

• 3809-32-3 2,5-dimethylcyclohexanol 
• 2748-10-9 3,6-dimethyl-1,2-cyclohexanedione 
• 861574-59-6 2-chloro-3,6-dimethyl-cyclohexanone 
• 2748-08-5 2-hydroxy-3,6-dimethyl-2-cyclohexenone 
• 110364-42-6 2-Hydroxy-2,5-dimethyl-cyclohexanone 
• 37720-04-0 2,5-Dimethyl-2-(3-propenyl)cyclohexanone 
• 2542-87-2 1,4-Dimethyl-3-hydroxymethylen-cyclohexanon-⁽²⁾ 
• 2808-79-9 1,4-dimethylcyclohex-1-ene 
• 59356-67-1 cis-3,6-dimethylcyclohexene 
• 19550-40-4 trans-3,6-dimethylcyclohexene 
• 61505-17-7 (+/-)-trichodiene 
• 61375-52-8 (2RS,1'SR)-2-(1',4'-dimethylcyclohex-3'-enyl)-2-methylcyclopentan-1-one 
• 74592-60-2 (1,4-Dimethyl-2-oxo-cyclohexyl)-acetaldehyde 
• 37720-03-9 1,4-Dimethyl-2-oxo-3-cyclohexeneacetic acid 

Relevant academic research and scientific papers

Epimerization and kinetic resolution in copper-catalyzed enantioselective 1,4-additions of organozinc reagents to 6-substituted cyclohex-2-enones

Enantioselective 1,4-addition reactions of diethyl-, dimethyl-, and di-n-butylzinc to 6-methylcyclohex-2-enone (1) and 6-t-butylcyclohex-2-enone (4), catalyzed by Cu(OTf)2 and phosphoramidites L1-L4 were examined. The additions to enone 1 proce

Selective deoximation using alumina supported potassium permanganate

Ketoximes are converted to the parent ketones in good yields when treated with potassium permanganate supported on neutral alumina (ASPP). An optimized procedure has been developed, the simple work-up minimizes loss of product and oximes have been selectively oxidized in the presence of alkenes.

Amidino derivatives useful as nitric oxide synthase inhibitors

The current invention discloses useful pharmaceutical compositions containing amidino derivative useful as nitric oxide synthase inhibitors.

Quantitative analyses of the seven isomeric 3,4- and 3,6-dimethylcyclohexenes by gas chromatography

Quantitative analyses of mixtures of the seven isomeric 3,4- and 3,6-dimethylcyclohexenes have been achieved by gas chromatography. Correlations of structure and absolute stereochemistry with elution order have been made rigorously with the aid of authentic optically active samples all derived from (3R)-methylcyclohexanone.

Amidino dervatives useful as nitric oxide synthase inhibitors

The current invention discloses useful pharmaceutical compositions containing azepine derivatives useful as nitric oxide synthase inhibitors.

Diastereo- and enantioselective synthesis of dimethylcyclohexanamines by asymmetric reductive amination

A series of optically active dimethylcyclohexanamines 6a-c, e, with ee values ranging from 86- > 99%, have been synthesised by asymmetric reductive amination of the corresponding racemic diastereomeric cyclohexanones 3a-c, e. Their conformation and configuration are also discussed.

Amphiphilic Reactions by Means of Exceptionally Bulky Organoaluminum Reagents. Rational Approach for Obtaining Unusual Equatorial, Anti-Cram, and 1,4 Selectivity in Carbonyl Alkylation

Exceptionally bulky, oxygenophilic organoaluminum reagents, methylaluminum bis(2,6-di-tert-4-alkylphenoxide) (MAD and MAT), have been successfully utilized for stereoselective activation of carbonyl moiety.Combination of MAD or MAT with carbon nucleophiles such as organolithiums or Grignard reagents generates a new amphiphilic reaction system in which the alkylation may be interpreted as the nucleophilic addition of a reactive organometallic compound to an electrophilically activated carbonyl substrate in order to account for the regio- and stereochemical consequences.In contrast to the ordinary alkylations, the amphilic alkylation disclosed herein would be categorized into the new, yet unexplored class of alkylation that exhibits high chemoselectivity to carbonyl compounds, and more significantly it allows excellent equatorial and anti-Cram selectivity in carbonyl alkylations, hitherto difficult by the existing methodologies.Further, unusual conjugate addition of organolithium reagents to α,β-unsaturated carbonyl compounds has been accomplished by using the amphiphilic reaction system.

UNUSUAL CONJUGATE ADDITION OF ORGANOLITHIUM REAGENT TO α,β-UNSATURATED KETONE

The conjugate addition of organolithium reagent to α,β-unsaturated ketone has been accomplished with methylaluminum bis(2,6-di-tert-butyl-4-alkylphenoxide) (MAD and MAT).Here combination of alkyllithium and MAD (or MAT) constitutes an amphiphilic system that allows to exhibit unusual selectivity in the alkylation of enones with alkyllithium.

Functionalization of Saturated Hydrocarbons. Part 4. The Gif System for Selective Oxidation using Molecular Oxygen

Various systems for the selective oxidation of saturated hydrocarbons have been developed.These are based on the idea of an iron catalyst which is reduced by electron transfer and oxidized by molecular oxygen simultaneously in the presence of a source of protons.Four modifications of this system (the Gif system) have been devised of which the best (Gif IV) consists of an iron catalyst with metallic zinc as the reductant, acetic acid as the proton source and pyridine as the solvent.At room temperature, using oxygen or air, saturated hydrocarbons are oxidized selectively to ketones in isolated yields superior to those reported for comparable model systems.

Polycyclic phenols, alcohols and ketones from phenols, cyclic alcohols and cyclic ketones using a nickel oxide/manganese oxide/magnesium oxide catalyst in presence of at least one of hydrogen and nitrogen

At least one of a polycyclic phenol, a polycyclic alcohol and a polycyclic ketone is produced under hydrogenation conditions using a nickel oxide/manganese oxide/magnesium oxide catalyst by subjecting at least one of a monocyclic ketone, a monocyclic alcohol and a monocyclic phenol to said conditions and said catalyst.