1042031-55-9

Basic information

• Product Name: 2-(4-methoxyphenyl)-1(2H)-6-methoxyisoquinolinone
• Synonyms: 2-(4-methoxyphenyl)-1(2H)-6-methoxyisoquinolinone
• CAS NO: 1042031-55-9
• Molecular Weight: 281.311
• Mol File: 1042031-55-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxyphenyl)-1(2H)-6-methoxyisoquinolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenyl)-1(2H)-6-methoxyisoquinolinone(1042031-55-9)
• EPA Substance Registry System: 2-(4-methoxyphenyl)-1(2H)-6-methoxyisoquinolinone(1042031-55-9)

Safety Data

• Hazardous Substances Data: 1042031-55-9(Hazardous Substances Data)

Upstream product

• 1223004-89-4 C₁₇H₁₇NO₂ 
• 43192-31-0 2-bromo-4-methoxybenzaldehyde 
• 90843-19-9 4-methoxy-2-vinylbenzaldehyde 
• 104-94-9 4-methoxy-aniline 
• 26829-43-6 6-methoxy-2H-isoquinolin-1-one 
• 696-62-8 para-iodoanisole 

Downstream Products

• 1042031-57-1 4-bromo-6-methoxy-2-(4-methoxyphenyl)isoquinolin-1(2H)-one 

Relevant articles and documents

Tandem Reaction Approaches to Isoquinolones from 2-Vinylbenzaldehydes and Anilines via Imine Formation-6π-Electrocyclization-Aerobic Oxidation Sequence

Two distinctive transition-metal-promoted aerobic oxidation protocols have been developed for the synthesis of isoquinolones from 2-vinylbenzaldehydes and aniline derivatives. Thus, the one-pot tandem reaction sequence of imine formation, thermal 6π-electrocyclization, followed by either Cu(OAc)2-mediated or Pd(OAc)2-catalyzed aerobic oxidation protocol allowed the ready access to isoquinolone derivatives. The control experiments revealed that the 1,2-dihydroisoquinoline intermediates from the 6π-electrocyclization of 1-azatrienes were aerobically oxidized to isoquinolones in the presence of either Cu(OAc)2 or Pd(OAc)2 catalyst.