104206-37-3

Upstream product

• 849100-15-8 (3-methoxy-5-oxo-4-trifluoromethanesulfonyloxy-5H-furan-2-ylidene)-(3,4,5-trimethoxy-phenyl)-acetic acid methyl ester 
• 5720-07-0 4-methoxyphenylboronic acid 
• 2989-06-2 methyl 2-(3,4,5-trimethoxyphenyl)acetate 
• 49829-96-1 3-methoxy-4-(4-methoxyphenyl)furan-2,5-dione 
• 110087-40-6 methyl α-<2-hydroxy-3-methoxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-yl>-3,4,5-trimethoxyphenylacetate 
• 110087-45-1 2-(4-methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-3,4-dioxoadiponitrile 
• 104-47-2 p-methoxybenzylnitrile 
• 13338-63-1 2-(3,4,5-trimethoxyphenyl)acetonitrile 
• 849100-11-4 1,2,3-Trimethoxy-5-{(E)-3-methoxy-1-[1-methoxy-1-trimethylsilanyloxy-meth-(E)-ylidene]-2-trimethylsilanyloxy-allyl}-benzene 
• 849100-13-6 (4-hydroxy-3-methoxy-5-oxo-5H-furan-2-ylidene)-(3,4,5-trimethoxy-phenyl)-acetic acid methyl ester 
• 849100-09-0 (Z)-4-Methoxy-2-(3,4,5-trimethoxy-phenyl)-3-trimethylsilanyloxy-but-2-enoic acid methyl ester 
• 849100-06-7 4-methoxy-3-oxo-2-(3,4,5-trimethoxy-phenyl)-butyric acid methyl ester 
• 186581-53-3 diazomethane 

Downstream Products

• 104222-55-1 iso-gomphidic acid 

Relevant academic research and scientific papers

Synthesis of natural pulvinic acids based on a '[3+2] cyclization-Suzuki cross-coupling' strategy

A number of pulvinic acid natural products were prepared based on Suzuki cross coupling reactions of α-hydroxy-γ-alkylidenebutenolides which are readily available by cyclization of 1,3-bis-silyl enol ethers with oxalyl chloride. The formal total synthesis

New Syntheses of Pulvinic Acids via Reformatsky-type Reactions with Aryl methoxymaleic Anhydrides

The reaction of zinc enolates, viz (13), derived from arylacetates with 2-aryl-3-methoxymaleic anhydrides gives β-hydroxy ester intermediates viz(17) which can be dehydrated to Z- and E-isomers of permethylated pulvinic acids.Thus, the intermediate (17) d