1043605-52-2

Upstream product

• 544-97-8 dimethyl zinc(II) 
• 132115-87-8 (4-trifluoromethyl-phenyl)carbonyl-acetic acid methyl ester 
• 1223410-65-8 (S)-(-)-2-[4-trifluoromethylphenyl]-4-phenylbut-3-yn-2-ol 
• 709-63-7 1-(4-trifluoromethylphenyl)ethanone 
• 1610048-68-4 C₁₇H₁₅F₃O 
• 67-56-1 methanol 
• 1610048-72-0 C₁₀H₉F₃O₂ 

Relevant academic research and scientific papers

Enantioselective addition of organozinc reagents to carbonyl compounds catalyzed by a camphor derived chiral γ-amino thiol ligand

In this article, the design and synthesis of the chiral camphor derived γ-amino thiol ligand 17 and its application in catalytic enantioselective carbon-carbon forming reactions through the addition of organozinc reagents to carbonyl compounds is described. The catalytic activity and enantioselectivity of ligand 17 is demonstrated in the enantioselective addition of various organozinc reagents to aldehydes and ketoesters, offering the corresponding alcohols in high yields and enantioselectivities. The role of the mercapto group in the highly enantioselective 1,2-addition reaction of organozincs to aldehyde is also discussed.

Lithium binaphtholate-catalyzed asymmetric addition of lithium acetylides to carbonyl compounds

The asymmetric addition of lithium acetylides to carbonyl compounds in the presence of a chiral lithium binaphtholate catalyst was developed. A procedure involving the slow addition of carbonyl compounds to lithium acetylides improved the enantioselectivi