132115-87-8

Basic information

• Product Name: (4-trifluoromethyl-phenyl)carbonyl-acetic acid methyl ester
• Synonyms: (4-trifluoromethyl-phenyl)carbonyl-acetic acid methyl ester
• CAS NO: 132115-87-8
• Molecular Weight: 232.159
• Mol File: 132115-87-8.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 66-68 °C(Press: 5 Torr)
• Density: 1.330±0.06 g/cm3(Predicted)
• CAS DataBase Reference: (4-trifluoromethyl-phenyl)carbonyl-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-trifluoromethyl-phenyl)carbonyl-acetic acid methyl ester(132115-87-8)
• EPA Substance Registry System: (4-trifluoromethyl-phenyl)carbonyl-acetic acid methyl ester(132115-87-8)

Safety Data

• Hazardous Substances Data: 132115-87-8(Hazardous Substances Data)

Usage

General Description

(4-trifluoromethyl-phenyl)carbonyl-acetic acid methyl ester is a chemical compound with the molecular formula C10H9F3O3. It is an ester derivative of (4-trifluoromethyl-phenyl)carbonyl-acetic acid, which is a white crystalline solid. (4-trifluoromethyl-phenyl)carbonyl-acetic acid methyl ester is often used as a building block in the synthesis of pharmaceuticals and agrochemicals. It has a variety of potential applications in the fields of medicine and agriculture, and its unique structure and properties make it a valuable tool in organic synthesis. Additionally, its trifluoromethyl group is known for its ability to influence the biological and pharmacokinetic properties of biologically active compounds. Overall, (4-trifluoromethyl-phenyl)carbonyl-acetic acid methyl ester is an important chemical compound with wide-ranging potential uses in various industries.

Upstream product

• 156276-22-1 methyl 2-hydroxy-2-(4-(trifluoromethyl)phenyl)acetate 
• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 67-56-1 methanol 
• 709-63-7 1-(4-trifluoromethylphenyl)ethanone 
• 556110-56-6 2,2-dibromo-1-(4-(trifluoromethyl)phenyl)ethan-1-one 
• 74-88-4 methyl iodide 
• 219564-85-9 methyl 4-trifluoromethylphenyldiazoacetate 
• 79478-02-7 4-(trifluoromethyl)phenylglyoxylic acid 
• 73183-23-0 2-(4-(trifluoromethyl)phenyl)-2-((trimethylsilyl)oxy)acetonitrile 
• 553-90-2 Dimethyl oxalate 
• 402-51-7 4-(trifluoromethyl)phenylmagnesium bromide 
• 5781-53-3 monomethyl oxalyl chloride 
• 2923-41-3 (4-(trifluoromethyl)phenyl)magnesium chloride 
• 7456-87-3 carbonic acid monomethyl ester 

Downstream Products

• 79478-02-7 4-(trifluoromethyl)phenylglyoxylic acid 
• 156276-22-1 methyl 2-hydroxy-2-(4-(trifluoromethyl)phenyl)acetate 
• 175605-64-8 1-(4-(trifluoromethyl)phenyl)ethane-1,2-diol 
• 1043605-52-2 (S)-(+)-methyl 2-hydroxy-2-[4-(trifluoromethyl)phenyl]propanoate 

Relevant articles and documents

Tris(pentafluorophenyl)borane-Catalyzed Oxygen Insertion Reaction of α-Diazoesters (α-Diazoamides) with Dimethyl Sulfoxide

A tris(pentafluorophenyl)borane-catalyzed oxidation reaction of α-diazoesters (α-diazo amides) with dimethyl sulfoxide has been developed. The reaction proceeds under metal free conditions to afford a series α-ketoesters and α-ketoamides. The synthetic utility of this protocol is demonstrated through synthetic transformations and scaled-up synthesis. (Figure presented.).

Tandem Photoredox-Chiral Phosphoric Acid Catalyzed Radical-Radical Cross-Coupling for Enantioselective Synthesis of 3-Hydroxyoxindoles

A photochemical protocol that couples diarylamines and α-ketoesters to afford the chiral 3-hydroxyoxindoles through tandem photoredox and chiral phosphoric acid catalysis is developed. The reaction involves an enantioselective photochemical radical-radical cross-coupling process. The chiral phosphoric acid is discovered to play crucial roles by decreasing the reductive potentials of α-ketoesters and stereocontrolling the downstream asymmetric radical-radical cross-coupling via the formation of pentacoordinate complex.

Amphiphilic fluorine-containing benzoyl formate photoinitiator suitable for LED photopolymerization and preparation method of amphiphilic fluorine-containing benzoyl formate photoinitiator

The invention discloses an amphiphilic fluorine-containing benzoyl formate photoinitiator suitable for LED photopolymerization, relates to the field of photosensitive macromolecules, and aims to solve the problems that an existing photoinitiator is poor in initiation performance under the irradiation of an LED light source and limited in application in the field of deep polymerization. The chemical structural general formula of the photoinitiator is shown in the specification, wherein R1 is selected from hydrogen, C1-C16 aliphatic groups, aralkyl, ether and aryl, R2, R3, R4, R5 and R6 are selected from hydrogen, fluorine and trifluoromethyl, but R2, R3, R4, R5 and R6 cannot be hydrogen at the same time. The invention also provides a preparation method of the photoinitiator and application of the photoinitiator in a photopolymerization system. The photoinitiator has the beneficial effects that the photoinitiator has proper absorption capacity in a visible light region, not only ensures higher photopolymerization rate under an LED light source, but also can be applied to deep polymerization, in addition, the photoinitiator is suitable for oily and water-based photopolymerization systems, does not contain ions, is wider in application range, and facilitated the development of the LED photopolymerization industry.