10440-82-1

Basic information

• Product Name: 5-[(4-methylphenyl)sulfonyl]-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline
• CAS NO: 10440-82-1
• Molecular Formula: C₁₇H₁₅N₃O₂S
• Molecular Weight: 325.3849
• Mol File: 10440-82-1.mol

Chemical Properties

• Boiling Point: 594.2°C at 760 mmHg
• Flash Point: 313.2°C
• Density: 1.401g/cm³
• Vapor Pressure: 4.33E-14mmHg at 25°C
• Refractive Index: 1.68
• CAS DataBase Reference: 5-[(4-methylphenyl)sulfonyl]-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(4-methylphenyl)sulfonyl]-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline(10440-82-1)
• EPA Substance Registry System: 5-[(4-methylphenyl)sulfonyl]-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline(10440-82-1)

Safety Data

• Hazardous Substances Data: 10440-82-1(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 529-23-7 o-aminobenzaldehyde 
• 1224713-12-5 N-(2-formylphenyl)-4-methyl-N-(prop-2-yn-1-yl)benzenesulfonamide 
• 6590-65-4 N-(2-Formyl-phenyl)-4-methyl-benzenesulfonamide 
• 19596-46-4 3-[1-Hydroxy-meth-(E)-ylidene]-1-(toluene-4-sulfonyl)-2,3-dihydro-1H-quinolin-4-one 
• 14278-37-6 1-tosyl-2,3-dihydroquinolin-4(1H)-one 

Relevant articles and documents

Intramolecular Cycloaddition Approach to Fused Pyrazoles: Access to 4,5-Dihydro-2 H -pyrazolo[4,3- c ]quinolines, 2,8-Dihydroindeno[2,1- c ]pyrazoles, and 4,5-Dihydro-2 H -benzo[ e ]indazoles

A straightforward and efficient method for the synthesis of pyrazoles fused with 1,2,3,4-tetrahydroquinoline, 2,3-dihydro-1 H -indene, or 1,2,3,4-tetrahydronaphthalene involves the formation of the tosylhydrazone from an aromatic substrate carrying aldehy

Antifertility Agents: Part XLIII - Synthesis of 3-Aryl-4,5-dihydro-2-substituted-5-tosyl-2H-pyrazoloquinolines and 2,4-Dihydro-3-phenylbenzopyranopyrazoles and Their Derivatives

2,3-Dihydro-1-tosyl-4(1H)-quinolones (5-7) on formylation give the corresponding 3-hydroxymethylene derivatives (11-13) of which 12 and 13 react with piperazine to afford N,N-bis-substituted piperazines (15 and 16).Refluxing of 11-13 with substituted hydr