104425-36-7

Basic information

• Product Name: acetic acid N-oxysuccinimide ester
• Synonyms: acetic acid N-oxysuccinimide ester
• CAS NO: 104425-36-7
• Molecular Weight: 393.226
• Mol File: 104425-36-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: acetic acid N-oxysuccinimide ester(CAS DataBase Reference)
• NIST Chemistry Reference: acetic acid N-oxysuccinimide ester(104425-36-7)
• EPA Substance Registry System: acetic acid N-oxysuccinimide ester(104425-36-7)

Safety Data

• Hazardous Substances Data: 104425-36-7(Hazardous Substances Data)

Upstream product

• 26159-34-2 Naprelan 
• 15307-79-6 diclofenac sodium 
• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 15307-86-5 [2-(2,6-dichloroanilino)phenyl]acetic acid 

Downstream Products

• 192377-01-8 {2-[2-(2,6-Dichloro-phenylamino)-phenyl]-acetylamino}-acetic acid methyl ester 
• 216875-76-2 (S)-2-{2-[2-(2,6-Dichloro-phenylamino)-phenyl]-acetylamino}-4-methylsulfanyl-butyric acid ethyl ester 
• 683748-94-9 C₁₈H₂₀Cl₂N₂O₃ 
• 216875-90-0 (2-{2-[2-(2,6-dichloro-phenylamino)-phenyl]-acetylamino}-acetylamino)-acetic acid methyl ester 
• 69630-31-5 acetylglycine 

Relevant articles and documents

Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis

We report the synthesis of a series of hybrid compounds incorporating 6- and 7-substituted coumarins (carbonic anhydrase, CA inhibitors) derivatized with clinically used NSAIDs (indomethacin, sulindac, ketoprofen, ibuprofen, diclofenac, ketorolac, etc., cyclooxygenase inhibitors) as agents for the management of rheumatoid arthritis (RA). Most compounds were effective in inhibiting the RA overexpressed hCA IX and XII, with KI values in the low nanomolar-subnanomolar ranges. The antihyperalgesic activity of such compounds was assessed by means of the paw-pressure and incapacitance tests using an in vivo RA model. Among all tested compounds, the 7-coumarine hybrid with ibuprofen showed potent and persistent antihyperalgesic effect up to 60 min after administration.

N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF

ABSTRACT Compounds that can be used as openers or blockers of voltage-dependent potassium channels, and which are useful in the treatment of conditions such as central or peripheral nervous system disorders through the modulation of potassium ion flux thr

Succinimide esters and glycine amides of non-steroidal antiinflammatory drugs

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