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26159-34-2

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Product FOB Price Min.Order Supply Ability Supplier
Naproxin Sodium
Cas No: 26159-34-2
No Data No Data Metric Ton/Day Lonwin Chemical Group Limited Contact Supplier
Naproxen sodium Manufacturer/High quality/Best price/In stock
Cas No: 26159-34-2
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
High quality Naproxen sodium with best price and good quality cas:26159-34-2
Cas No: 26159-34-2
USD $ 80.0-100.0 / Kilogram 1 Kilogram 99999 Kilogram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
naproxen sodium
Cas No: 26159-34-2
USD $ 1.0-1.0 / Gram 1000 Gram 10 Metric Ton/Month Hebei yanxi chemical co.,LTD. Contact Supplier
High quality USP Naproxen sodium Cas 26159-34-2 with high purity 99% and best price
Cas No: 26159-34-2
No Data 25 Kilogram 100 Metric Ton/Year Wuhan Fortuna Chemical Co.,Ltd Contact Supplier
CHemwill -- Naproxen sodium
Cas No: 26159-34-2
USD $ 1.0-1.0 / Metric Ton 1 Metric Ton 5 Metric Ton/Day Chemwill Asia Co., Ltd. Contact Supplier
High quality Naproxen Sodium supplier in China
Cas No: 26159-34-2
No Data No Data No Data Simagchem Corporation Contact Supplier
Naproxen Sodium factory price
Cas No: 26159-34-2
No Data 1 Kilogram 300 Kilogram/Month HENAN SUNLAKE ENTERPRISE CORPORATION Contact Supplier
High purity Naproxen Sodium in stock factory
Cas No: 26159-34-2
No Data 1 Gram 1 Metric Ton/Month Shaanxi Mingqi Chemical Co., Ltd Contact Supplier
Pharmaceutical Diclofenac Sodium CAS 26159-34-2 for Anti-Inflammatory
Cas No: 26159-34-2
No Data 100 Gram 20000 Kilogram/Day Hubei XinRunde Chemical Co., Ltd Contact Supplier

26159-34-2 Usage

Brand name

Aleve (Bayer); Anaprox (Roche);Naprelan (Stat Trade).

Non-steroidal anti-inflammatory analgesic

Naproxen sodium is a non-steroidal anti-inflammatory analgesic drug which is more tolerable to human, belonging to the phenylpropionic acid compounds. It plays anti-inflammatory effect by inhibiting prostaglandin synthesis.It is absorbed rapidly after oral administration and the plasma reached the peak concentration within 2 to 4 hours. Food has little effect on the rate of absorption. Naproxen and plasma protein are highly binded(99%); the plasma concentration is between 23~40mcg/ml. The metabolic process is demethylation and then combining with glucuronide; the elimination half-life is 12 to 15 hours, mainly excreted by the urine. Clinical application is to relieve a variety of mild to moderate degree of pain, such as tooth extraction and other postoperative pain, primary dysmenorrhea and headache. It is also used for rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, juvenile arthritis, tendinitis, bursitis and acute gouty arthritis; it also plays a role in arthritis pain, swelling and activity restricted symptom. Psoriatic arthritis and Reiter's syndrome can also be treated with this product. Compared with ibuprofen, fenoprofen, aspirin, sulindac and indomethacin, the symptom relief effect was similar, but the incidence and severity of adverse reactions in the gastrointestinal and neurological systems were low. In addition, this product is also the same as aspirin which can inhibit platelet aggregation and prolong bleeding time; but the effect is reversible, and can be restored after stopping.
Naproxen sodium and plasma protein binding rate is high (99%), and other protein-binding drugs can be replaced by its joint out. Therefore, the acceptance of these drugs (such as oral anticoagulants, sulfonylurea, hydantoins) people should observe the interaction effects. At the same time the application of probenecid, naproxen can increase the plasma concentration, half-life period. Magnesium hydroxide, aluminum can make this product absorption rate slightly lower; sodium bicarbonate can make it higher.

Biological Activity

Non-selective cyclooxygenase (COX) inhibitor that displays anti-inflammatory, antipyretic and analgesic effects. Has a neuroprotective role against colchicine-induced cognitive impairment and oxidative stress.

Uses

An anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory

Uses

Used as anti-inflammatory analgesic

Chemical Properties

White Powder

Definition

ChEBI: The sodium salt of naproxen.

Uses

Naproxen (Aleve, Anaprox) is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively
InChI:InChI=1/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1

26159-34-2 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Sigma (M1275)  Naproxensodium  98.0-102.0% 26159-34-2 M1275-50G 3,834.09CNY Detail
Sigma (M1275)  Naproxensodium  98.0-102.0% 26159-34-2 M1275-25G 2,228.85CNY Detail
Sigma (M1275)  Naproxensodium  98.0-102.0% 26159-34-2 M1275-5G 766.35CNY Detail
USP (1457403)  Naproxensodium  United States Pharmacopeia (USP) Reference Standard 26159-34-2 1457403-200MG 4,588.74CNY Detail
Sigma-Aldrich (PHR1165)  Naproxensodium  pharmaceutical secondary standard; traceable to USP 26159-34-2 PHR1165-1G 878.44CNY Detail

26159-34-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name naproxen sodium

1.2 Other means of identification

Product number -
Other names Naproxen sodium

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:26159-34-2 SDS

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